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L-Arginine-15N4 hydrochloride
(Synonyms: L-Arginine-15N4 hydrochloride, (S)-(+)-Arginine-15N4 hydrochloride) Copy Product Info
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Synonyms: L-Arginine-15N4 hydrochloride, (S)-(+)-Arginine-15N4 hydrochloride
Catalog No. T39441 Copy Product Info
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L-Arginine-15N4 hydrochloride, the 15N-labeled variant of L-Arginine hydrochloride (T0670), serves as the nitrogen donor in the synthesis of nitric oxide. This potent vasodilator is crucial, especially during a sickle cell crisis where its levels are notably diminished.
Cas No. 204633-95-4
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Product Introduction
Bioactivity
Chemical Properties
Storage & Solubility Information
| Description | L-Arginine-15N4 hydrochloride, the 15N-labeled variant of L-Arginine hydrochloride (T0670), serves as the nitrogen donor in the synthesis of nitric oxide. This potent vasodilator is crucial, especially during a sickle cell crisis where its levels are notably diminished. |
| In vitro | Stable heavy isotopes of hydrogen, carbon, and other elements are incorporated into drug molecules primarily as tracers for quantification throughout the drug development process. Deuteration is noteworthy for its ability to alter the pharmacokinetic and metabolic profiles of drugs[1]. |
| Synonyms | L-Arginine-15N4 hydrochloride, (S)-(+)-Arginine-15N4 hydrochloride |
| Molecular Weight | 214.63 |
| Formula | C6H15ClN4O2 |
| Cas No. | 204633-95-4 |
| Smiles | Cl.[15NH2][C@@H](CCC[15NH]C([15NH2])=[15NH])C(O)=O |
| Relative Density. | no data available |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, and a total of 10 animals are to be administered, using a formulation of 
10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.Stock Solution Preparation:
Dissolve 2 mg of the compound in 100 μL DMSO to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
Preparation of the In Vivo Formulation:
1) Add 100 μL of the DMSO stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.
2) Add 50 µL Tween 80 and mix well until fully clarified.
3) Add 450 µL Saline,PBS or ddH2O and mix thoroughly until a homogeneous solution is obtained.
This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: L-Arginine-15N4 hydrochloride chemical structure | L-Arginine-15N4 hydrochloride in vitro | L-Arginine-15N4 hydrochloride formula | L-Arginine-15N4 hydrochloride molecular weight
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