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Kynurenic acid sodium
🥰Excellent
Catalog No. T22892Cas No. 2439-02-3
Alias Kynurenic acid sodium salt
Kynurenic acid sodium salt is an endogenous tryptophan metabolite that acts as a broad-spectrum antagonist targeting ionotropic glutamate receptors (NMDA), other glutamate receptors, and the α7 nicotinic acetylcholine receptor, while also functioning as a potent agonist for the G-protein coupled receptor GPR35/CXCR8.
Kynurenic acid sodium
🥰Excellent
Purity: 99.47%
Catalog No. T22892Alias Kynurenic acid sodium saltCas No. 2439-02-3
Kynurenic acid sodium salt is an endogenous tryptophan metabolite that acts as a broad-spectrum antagonist targeting ionotropic glutamate receptors (NMDA), other glutamate receptors, and the α7 nicotinic acetylcholine receptor, while also functioning as a potent agonist for the G-protein coupled receptor GPR35/CXCR8.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $29 | In Stock | |
| 50 mg | $30 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $40 | In Stock |
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Purity:99.47%
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Product Introduction
Bioactivity
Chemical Properties
| Description | Kynurenic acid sodium salt is an endogenous tryptophan metabolite that acts as a broad-spectrum antagonist targeting ionotropic glutamate receptors (NMDA), other glutamate receptors, and the α7 nicotinic acetylcholine receptor, while also functioning as a potent agonist for the G-protein coupled receptor GPR35/CXCR8. |
| In vitro | Methods: Corneal epithelial cells and conjunctival epithelial cells were treated with Kynurenic acid sodium (1-100 μM, 24-48 hours), and cell viability was determined by MTT assay. Results: Kynurenic acid sodium caused a concentration-dependent decrease in the metabolic activity of these cells. [1] |
| Synonyms | Kynurenic acid sodium salt |
| Molecular Weight | 211.15 |
| Formula | C10H6NNaO3 |
| Cas No. | 2439-02-3 |
| Smiles | O=C(C1=CC(O)=C2C=CC=CC2=N1)[O-].[Na+] |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from moisture,store under nitrogen,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. | |||||||||||||||||||||||||||||||||||
| Solubility Information | H2O: < 0.1 mg/mL (insoluble) DMSO: 40 mg/mL (189.44 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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