Shopping Cart

Your shopping cart is currently empty

Lanoconazole

Name: Lanoconazole
Brand: TargetMol
SKU: T15708
Price: 49 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T15708Cas No. 101530-10-3

Alias TJN318, NND-318, NND318, M-110101, M-1100, M1100

Lanoconazole is an antifungal imidazole drug used primarily for the treatment of fungal skin infections that is potent and orally available. It acts by inhibiting the synthesis of ergosterol in fungal cell membranes, increasing the permeability of fungal cell membranes, leading to cell lysis and death. Lanoconazole exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., and Candida spp..

Lanoconazole

🥰Excellent

Purity: 98%

Catalog No. T15708Alias TJN318, NND-318, NND318, M-110101, M-1100, M1100Cas No. 101530-10-3

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
2 mg	$49	-	In Stock

Add to Cart

Add to Quotation

In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98%

Resource Download

COA

Product Introduction

Bioactivity

Description	Lanoconazole is an antifungal imidazole drug used primarily for the treatment of fungal skin infections that is potent and orally available. It acts by inhibiting the synthesis of ergosterol in fungal cell membranes, increasing the permeability of fungal cell membranes, leading to cell lysis and death. Lanoconazole exhibits potent antifungal activity against a wide range of pathogenic fungi including yeast, dermatophytes, dermatiaceous fungi, dimorphic fungi, Aspergihs spp., and Candida spp..
In vivo	Lanoconazole (3, 10, or 30 mg/kg, orally, once daily for 3 weeks) significantly reduces the growth of C. neoformans in the lungs and brain of mice.[3]
Synonyms	TJN318, NND-318, NND318, M-110101, M-1100, M1100

Chemical Properties

Molecular Weight	319.83
Formula	C₁₄H₁₀ClN₃S₂
Cas No.	101530-10-3
Smiles	C(\C#N)(=C/1\SC(CS1)C2=C(Cl)C=CC=C2)/N3C=CN=C3
Relative Density.	1.43 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80 mg/mL (250.13 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (10.32 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.1267 mL	15.6333 mL	31.2666 mL	156.3331 mL
5 mM	0.6253 mL	3.1267 mL	6.2533 mL	31.2666 mL
10 mM	0.3127 mL	1.5633 mL	3.1267 mL	15.6333 mL
20 mM	0.1563 mL	0.7817 mL	1.5633 mL	7.8167 mL
50 mM	0.0625 mL	0.3127 mL	0.6253 mL	3.1267 mL
100 mM	0.0313 mL	0.1563 mL	0.3127 mL	1.5633 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc