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L-Ascorbic acid sodium salt (Standard) (Synonyms: Vitamin C sodium salt (Standard), Sodium ascorbate (Standard))

Name: L-Ascorbic acid sodium salt (Standard)
Brand: TargetMol
SKU: TMSM-1440
Rating: 4.5 (1 reviews)

Catalog No. TMSM-1440 Copy Product Info

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L-Ascorbic acid sodium salt (Standard) is the analytical standard of sodium ascorbate, primarily utilized for quantitative determination and bioanalytical research. Sodium ascorbate is a potent endogenous antioxidant and an essential electron donor involved in numerous biosynthetic pathways. It functions as a selective inhibitor of Cav3.2 channels (T-type calcium channels) with an IC50 of 6.5 μM. Furthermore, it acts as a significant modulator of the extracellular matrix, serving as a promoter of collagen deposition and an inhibitor of elastogenesis, making it a vital component in tissue engineering and dermatological studies.

L-Ascorbic acid sodium salt (Standard)

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Catalog No. TMSM-1440

Synonyms Vitamin C sodium salt (Standard), Sodium ascorbate (Standard)

Cas No. 134-03-2

Pack Size	Price	USA Stock	Global Stock	Quantity
100 mg	$36	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Appearance:Solid

Color:White

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COA

Product Introduction

Bioactivity

Description	L-Ascorbic acid sodium salt (Standard) is the analytical standard of sodium ascorbate, primarily utilized for quantitative determination and bioanalytical research. Sodium ascorbate is a potent endogenous antioxidant and an essential electron donor involved in numerous biosynthetic pathways. It functions as a selective inhibitor of Cav3.2 channels (T-type calcium channels) with an IC50 of 6.5 μM. Furthermore, it acts as a significant modulator of the extracellular matrix, serving as a promoter of collagen deposition and an inhibitor of elastogenesis, making it a vital component in tissue engineering and dermatological studies.
Targets&IC50	Cav 3.2:6.5 μM
Synonyms	Vitamin C sodium salt (Standard), Sodium ascorbate (Standard)

Chemical Properties

Molecular Weight	198.11
Formula	C₆H₇NaO₆
Cas No.	134-03-2
Smiles	[O-]C[C@@H]([C@]1([H])C(O)=C(C(O1)=O)O)O.[Na+]
Relative Density.	1.88. Temperature:19.7 °C.

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: < 1?mg/mL?(insoluble), Sonication is recommended.

H2O: 80 mg/mL (403.82 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	5.0477 mL	25.2385 mL	50.4770 mL	252.3850 mL
5 mM	1.0095 mL	5.0477 mL	10.0954 mL	50.4770 mL
10 mM	0.5048 mL	2.5239 mL	5.0477 mL	25.2385 mL
20 mM	0.2524 mL	1.2619 mL	2.5239 mL	12.6193 mL
50 mM	0.1010 mL	0.5048 mL	1.0095 mL	5.0477 mL
100 mM	0.0505 mL	0.2524 mL	0.5048 mL	2.5239 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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