IRL-1038 acetate

Name: IRL-1038 acetate
Brand: TargetMol
SKU: TP2262L
Rating: 4.5 (1 reviews)

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Catalog No. TP2262L

Alias IRL-1038 acetate(144602-02-8 Free base)

IRL-1038 acetate is a potent ETB endothelin receptor antagonist.

IRL-1038 acetate

😃Good

Catalog No. TP2262LAlias IRL-1038 acetate(144602-02-8 Free base)

IRL-1038 acetate is a potent ETB endothelin receptor antagonist.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$431	Inquiry	Inquiry
5 mg	$996	Inquiry	Inquiry
10 mg	$1,490	Inquiry	Inquiry
25 mg	$2,550	Inquiry	Inquiry
50 mg	$3,430	Inquiry	Inquiry

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	IRL-1038 acetate is a potent ETB endothelin receptor antagonist.
Synonyms	IRL-1038 acetate(144602-02-8 Free base)

Chemical Properties

Molecular Weight	1469.73
Formula	C₇₀H₉₆N₁₄O₁₇S₂
Smiles	O=C([C@H]1NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CSSC1)N)=O)C(C)C)=O)CC2=CC=C(C=C2)O)=O)CC3=CC=CC=C3)=O)N[C@@H](CC4=CN=CN4)C(N[C@@H](CC(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC5=CNC6=CC=CC=C56)=O)=O)=O)=O)=O.CC(O)=O
Relative Density.	no data available
Sequence	[Cys1-Cys5] Cys-Val-Tyr-Phe-Cys-His-Leu-Asp-Ile-Ile-Trp
Sequence Short	CVYFCHLDIIW

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc