keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-wound healing, and induces IL-8 secretion, in human colorectal cancer (HT29) cellsin vitro.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
5 mg | Inquiry | $ 970.00 |
Description | AY 254 is a potent PAR2 biased agonist. Selectively activates ERK1/2 signaling (EC50= 2 nM for ERK1/2 phosphorylation versus 80 nM for Ca2+release). Reduces cytoKi ne-induced caspase 3/8 activation, promotes scratch-wound healing, and induces IL-8 secretion, in human colorectal cancer (HT29) cellsin vitro. |
Molecular Weight | 631.779 |
Formula | C30H49N9O6 |
CAS No. | 2093408-03-6 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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AY 254 2093408-03-6 AY254 AY-254 inhibitor inhibit