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FINO2

Name: FINO2
Brand: TargetMol
SKU: T60084
Price: 52 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T60084Cas No. 869298-31-7

FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.

FINO2

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Purity: 97.27%

Catalog No. T60084Cas No. 869298-31-7

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$52	-	In Stock
5 mg	$129	In Stock	In Stock
10 mg	$213	In Stock	In Stock
25 mg	$359	In Stock	In Stock
50 mg	$533	-	In Stock
100 mg	$759	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.27%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.
In vitro	FINO2 (10 µM; 24 h) induces ferroptosis in HT-1080 cells, demonstrating the iron dependency of lipid peroxidation [1].

Chemical Properties

Molecular Weight	256.38
Formula	C₁₅H₂₈O₃
Cas No.	869298-31-7
Smiles	CC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1
Relative Density.	1.02 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 90 mg/mL (351.04 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9005 mL	19.5023 mL	39.0046 mL	195.0230 mL
5 mM	0.7801 mL	3.9005 mL	7.8009 mL	39.0046 mL
10 mM	0.3900 mL	1.9502 mL	3.9005 mL	19.5023 mL
20 mM	0.1950 mL	0.9751 mL	1.9502 mL	9.7512 mL
50 mM	0.0780 mL	0.3900 mL	0.7801 mL	3.9005 mL
100 mM	0.0390 mL	0.1950 mL	0.3900 mL	1.9502 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc