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FINO2

🥰Excellent
Catalog No. T60084Cas No. 869298-31-7

FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.

FINO2

FINO2

🥰Excellent
Purity: 97.27%
Catalog No. T60084Cas No. 869298-31-7
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
1 mg$52-In Stock
5 mg$129-In Stock
10 mg$213-In Stock
25 mg$359-In Stock
50 mg$533-In Stock
100 mg$759-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
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Purity:97.27%
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Product Introduction

Bioactivity
Description
FINO2 is a potent ferroptosis-inducing compound that inhibits GPX4 activity. It functions as a stable oxidant, effectively oxidizing ferrous iron and demonstrating stability across varying pH levels. Furthermore, FINO2 induces widespread lipid peroxidation.
In vitro
FINO2 (10 µM; 24 h) induces ferroptosis in HT-1080 cells, demonstrating the iron dependency of lipid peroxidation [1].
Chemical Properties
Molecular Weight256.38
FormulaC15H28O3
Cas No.869298-31-7
SmilesCC(C)(C)[C@H]1CC[C@]2(CC(C)(CCO)OO2)CC1
Relative Density.1.02 g/cm3 (Predicted)
Storage & Solubility Information
Storagestore at low temperature,keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 90 mg/mL (351.04 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.9005 mL19.5023 mL39.0046 mL195.0230 mL
5 mM0.7801 mL3.9005 mL7.8009 mL39.0046 mL
10 mM0.3900 mL1.9502 mL3.9005 mL19.5023 mL
20 mM0.1950 mL0.9751 mL1.9502 mL9.7512 mL
50 mM0.0780 mL0.3900 mL0.7801 mL3.9005 mL
100 mM0.0390 mL0.1950 mL0.3900 mL1.9502 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

FINO-2FINO2FINO 2Ferroptosis
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