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L162389

L162389
L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.
Catalog No. T11808Cas No. 169281-53-2
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Purity:99.68%
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L162389

Catalog No. T11808Cas No. 169281-53-2

L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
1 mg$333In Stock
5 mg$790In Stock
10 mg$1,120In Stock
25 mg$1,670In Stock
50 mg$2,180In Stock
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Product Introduction

Bioactivity
Description
L162389 is an orally active and potent angiotensin II receptor antagonist with a balanced affinity for AT1 and AT2 receptor subtypes that stimulates the conversion of phosphatidylinositol.
Targets&IC50
AT1 receptor:28 nM (Ki)
In vitro
METHODS: To determine the characteristics of the non-peptide angiotensin AT1 ligand L162389, a series of affinity assay studies were conducted.
RESULTS: L162389 also stimulated phosphatidylinositol turnover, although only a minor fraction of the angiotensin response, acting as an angiotensin antagonist with an IC50 of 105 nM [1].
AliasL 162389, L-162389
Chemical Properties
Molecular Weight562.72
FormulaC31H38N4O4S
Cas No.169281-53-2
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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