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α-Glucosidase-IN-105 is a selective and potent inhibitor of α-glucosidase with an IC50 of 31.36 μM. It also inhibits α-amylase (IC50: 104.2 μM). The inhibitory effects of α-Glucosidase-IN-105 are comparable to those of the standard drug Acarbose. This compound is useful in research related to type 2 diabetes.
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|---|---|---|---|---|
| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | α-Glucosidase-IN-105 is a selective and potent inhibitor of α-glucosidase with an IC50 of 31.36 μM. It also inhibits α-amylase (IC50: 104.2 μM). The inhibitory effects of α-Glucosidase-IN-105 are comparable to those of the standard drug Acarbose. This compound is useful in research related to type 2 diabetes. |
| Targets&IC50 | α-glucosidase:31.36 μM |
| In vitro | α-Glucosidase-IN-105 (Compound 6c) demonstrates α-amylase inhibitory activity with an IC50 value of 104.2 μM. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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