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Mal-VC-PAB-EDA-N-Ac-Calicheamicin
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Catalog No. T206389Cas No. 2028299-61-6
Mal-VC-PAB-EDA-N-Ac-Calicheamicin is a drug-linker conjugate for ADCs, exhibiting potent antitumor activity. OncoFAP-GlyPro-MMAF is composed of the ADC toxin Calicheamicin and a linker. It is used in the synthesis of the ADC molecule PF-06647263.
Mal-VC-PAB-EDA-N-Ac-Calicheamicin
😃Good
Catalog No. T206389Cas No. 2028299-61-6
Mal-VC-PAB-EDA-N-Ac-Calicheamicin is a drug-linker conjugate for ADCs, exhibiting potent antitumor activity. OncoFAP-GlyPro-MMAF is composed of the ADC toxin Calicheamicin and a linker. It is used in the synthesis of the ADC molecule PF-06647263.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | Backorder | |
| 50 mg | Inquiry | Backorder |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Mal-VC-PAB-EDA-N-Ac-Calicheamicin is a drug-linker conjugate for ADCs, exhibiting potent antitumor activity. OncoFAP-GlyPro-MMAF is composed of the ADC toxin Calicheamicin and a linker. It is used in the synthesis of the ADC molecule PF-06647263. |
| Molecular Weight | 2119.17 |
| Formula | C93H128IN11O31S3 |
| Cas No. | 2028299-61-6 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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