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Anti-Mouse Ter-119 Antibody (TER-119) is an IgG2b, κ immunoglobulin inhibitor derived from rats, targeting mouse Ter-119.

Peginterferon alfa-2b (Sch 54031), a recombinant alfa-2b interferon covalently bonded to polyethylene glycol (PEG), acts as an immunomodulator. This compound is effective in reducing viral DNA in HIV and has potential applications in melanoma research [1] [2].

Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft), a monopegylated interferon-alpha (IFN-α), is used in the study of myeloproliferative neoplasms [1].

Cepeginterferon alfa-2b, a pegylated interferon, features a polyethylene glycol (PEG) base with a molecular weight of 20 kDa. This compound is utilized in the research of numerous diseases, including hepatitis C virus (HCV), polycythemia vera (PV), and essential thrombocythemia (ET) [1] [2].

Teropavimab (3BNC117-LS), an antibody, is utilized in the research of HIV infection [1].

Sotatercept (ACE-011) is an activin receptor type IIA-Fc (ActRIIA-Fc) fusion protein and inhibitor of activin signaling.Sotatercept can be used in the study of pulmonary arterial hypertension.

Interferon alfa, a type I interferon, activates new genes, displaying strong antiviral and antiproliferative effects on target cells. It signals through receptor-mediated activation of Stat1 and Stat2, which heterodimerize into a STAT complex binding with the DNA-binding protein IRF-9 (p48) to form ISGF-3 (IFN-stimulated gene factor 3). This complex further activates driver genes to fulfill its antiviral role [1].

Luspatercept (ACE-536), a recombinant modified ActRIIB fusion protein, selectively binds to transforming growth factor β superfamily ligands, thereby enhancing erythrocyte production and advancing the maturation of erythroid precursors. Moreover, by binding with GDF11, it inhibits Smad2/3 signaling. This compound is instrumental in anemia research [1].

Mipeginterferon alfa-2b, an analog of interferon alpha-2b (IFNA2B), features an average substitution of 5 among its 11 amino groups (one N-terminal and 10 lysine N6), and exhibits a relative molecular mass of 40 kDa [1].

Rimteravimab (XVR011) is a bivalent VHH-Fc antibody that targets the disease caused by SARS-CoV-2, exhibiting potent neutralizing activity, high stability, broad coverage, and silenced Fc effector functions [1].

Farletuzumab ecteribulin (MORAb-202) is a highly cytotoxic antibody-drug conjugate (ADC) targeting human folate receptor alpha (FRA). This ADC comprises the humanized Farletuzumab antibody linked to Mal-PEG2-Val-Cit-PAB-eribulin through reduced interchain disulfide bonds, with an agent-to-antibody ratio of 4.0, demonstrating potent antitumor activity against FRA-positive cells in vitro.

Peginterferon lambda-1a (BMS-914143) is a monoclonal antibody targeting IFNLR1, composed of IFNL1 conjugated to pegol [1].

Sampeginterferon beta-1a (BCD-054), a pegylated IFNβ-1a, is evaluated for its potential in research addressing remitting multiple sclerosis [1] [2].

Remternetug (LY3372993) is a humanised monoclonal antibody targeting N3pG-Aβ, recognising pyroglutamated Aβ within amyloid plaques, applicable for Alzheimer's disease.

Peginterferon alfacon-2 is a human antibody targeting IFNAR1/2 [1].

Efmitermant alfa (ACE-083), a follistatin-based fusion protein with localized action, functions as a muscle-promoting agent and is utilized in the study of muscle disorders [1] [2].

Albinterferon alfa-2B (alb-IFN), a recombinant protein, comprises interferon alfa-2b conjugated to human albumin and is utilized in the study of chronic hepatitis C [1].

Anti-Rat FcRn heavy chain heterodimers Antibody (2G3) is an IgG1 antibody inhibitor derived from mice, specifically targeting rat FcRn heavy chain heterodimers.

Armenian hamster IgG, Isotype Control, is an IgG antibody inhibitor derived from Armenian hamster. It serves as an isotype control.

Anti-RatFcRnheavy chain heterodimers Antibody (1G3) is a mouse-derived antibody, specifically targeting the FcRn heavy chain heterodimers. The isotype control for Anti-RatFcRnheavy chain heterodimers Antibody (1G3) is designated as MouseIgG1kappa, Isotype Control.

Cibotercept is a monoclonal antibody targeting MSTN, INHBA, and GDF11.

Elritercept (KER-050) is a recombinant fusion protein composed of a modified extracellular domain of the activin receptor type IIA fused to human IgG1 Fc. It functions by inhibiting activin A and other specific ligands of the TGF-β superfamily.

C1 Esterase Inhibitor (Human) is a glycoprotein derived from human plasma and acts as a serine protease inhibitor. It inactivates enzymes like C1r, C1s, and mannose-binding lectin-associated serine proteases (MASP) through covalent binding. This compound possesses anti-inflammatory properties and is utilized to prevent angioedema attacks associated with hereditary angioedema.

Syrian Hamster IgG, Isotype Control, is an antibody derived from the Syrian hamster, serving as an isotype control for Syrian Hamster IgG antibodies.