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Rovatirelin

Name: Rovatirelin
Brand: TargetMol
SKU: T34399
Price: 223 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T34399Cas No. 204386-76-5

Alias S-0373, S0373, S 0373, KPS-0373

Rovatirelin (S-0373) is a newly synthesized thyrotropin-releasing hormone (TRH) analog that ameliorates cytosine arabinoside-induced motor dysfunction in a rat model of spinal cerebellar degeneration via acetylcholine and dopamine neurotransmission.

Rovatirelin

🥰Excellent

Purity: 99.59%

Catalog No. T34399Alias S-0373, S0373, S 0373, KPS-0373Cas No. 204386-76-5

Pack Size	Price	Availability
1 mg	$223	In Stock
5 mg	$536	In Stock
10 mg	$732	In Stock
25 mg	$1,090	In Stock

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This molecule is a custom-made product. TargetMol has an excellent synthesis team with the experience and capability to provide you with cost-effective products. However, due to objective factors, there is a small probability that the synthesis may not be successful during the R&D process. We appreciate your understanding. If you have any questions, please feel free to contact us. We are committed to serving you wholeheartedly.

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Purity:99.59%

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Rovatirelin (S-0373) is a newly synthesized thyrotropin-releasing hormone (TRH) analog that ameliorates cytosine arabinoside-induced motor dysfunction in a rat model of spinal cerebellar degeneration via acetylcholine and dopamine neurotransmission.
Synonyms	S-0373, S0373, S 0373, KPS-0373

Chemical Properties

Molecular Weight	366.43
Formula	C₁₆H₂₂N₄O₄S
Cas No.	204386-76-5
Smiles	[C@@H](C(=O)N1[C@H](C)CCC1)(CC2=CSC=N2)NC(=O)[C@@H]3[C@H](C)OC(=O)N3
Relative Density.	1.315 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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