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Anti-IL-28B Antibody (2R608) (Synonyms: interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B)

Catalog No. TMAY-02137 Copy Product Info
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Anti-IL-28B Antibody (2R608) is a Rabbit antibody targeting IL-28B. Anti-IL-28B Antibody (2R608) can be used in ELISA.

Anti-IL-28B Antibody (2R608)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02137
Synonyms interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B

Anti-IL-28B Antibody (2R608) is a Rabbit antibody targeting IL-28B. Anti-IL-28B Antibody (2R608) can be used in ELISA.

Anti-IL-28B Antibody
(2R608)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-28B Antibody (2R608) is a Rabbit antibody targeting IL-28B. Anti-IL-28B Antibody (2R608) can be used in ELISA.
Synonymsinterferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B
Ig Type
Rabbit IgG
Clone
2R608
Reactivity
Human
Specificity
Human IL-28B/Interferon lambda-3
Application
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human IL-28B / IFN-lambda-3 (rh IL-28B / IFN-lambda-3; TMPY-01872; NP_742151.2; Met1-Val196).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundInterleukin-28B (IL-28B) also known as Interferon lambda-3 and IFN-lambda-3, belongs to the type III interferon family of cytokines and are highly similar to IL-29. IL-28B belongs to the newly described interferon lambda (IFNλ) family of cytokines. IL-28B is a cytokine with immunomodulatory activity. It functions in Up-regulating MHC class I antigen expression. IL-28B displays potent antiviral activity and antitumor activity. This cytokine serves as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-28B, like IL-12, is capable of robustly enhancing adaptive immunity. Moreover, we describe for the first time how IL-28B reduces regulatory T-cell populations during DNA vaccination, whereas IL-12 increases this cellular subset. We also show that IL-28B, unlike IL-12, can increase the percentage of splenic CD8+ T cells in vaccinated animals and that these cells are more granular and have higher antigen-specific cytolytic degranulation compared with cells taken from animals that received IL-12 as an adjuvant.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IL-28B / IFN-lambda-3 protein (TMPY-01872)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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