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Anti-SLC22A1 Antibody (6Q395) is a Mouse antibody targeting SLC22A1. Anti-SLC22A1 Antibody (6Q395) can be used in FCM,WB.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $426 | 7-10 days |
Description | Anti-SLC22A1 Antibody (6Q395) is a Mouse antibody targeting SLC22A1. Anti-SLC22A1 Antibody (6Q395) can be used in FCM,WB. |
Synonyms | Solute carrier family 22 member 1, solute carrier family 22 (organic cation transporter), member 1, Slc22a1, S22A1_HUMAN, Organic cation transporter 1, oct1_cds, OCT1, hOCT1 |
Clone | 6Q395 |
Reactivity | Human |
Verified Activity | 1. Western blot analysis of SLC22A1 on HEK293 (1) and SLC22A1-hIgGFc transfected HEK293 (2) cell lysate using anti-SLC22A1 antibody at 1/1,000 dilution. 2. Flow cytometric analysis of Jurkat cells with SLC22A1 antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; purple). |
Application | |
Recommended Dose | WB: 1:500-1000; FCM: 1:100-200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide. |
Research Background | The transport of organic cations is inhibited by a broad array of compounds like tetramethylammonium (TMA), cocaine, lidocaine, NMDA receptor antagonists, atropine, prazosin, cimetidine, TEA and NMN, guanidine, cimetidine, choline, procainamide, quinine, tetrabutylammonium, and tetrapentylammonium. Translocates organic cations in an electrogenic and pH-independent manner. Translocates organic cations across the plasma membrane in both directions. Transports the polyamines spermine and spermidine. Transports pramipexole across the basolateral membrane of the proximal tubular epithelial cells. The choline transport is activated by MMTS. Regulated by various intracellular signaling pathways including inhibition by protein kinase A activation, and endogenously activation by the calmodulin complex, the calmodulin-dependent kinase II and LCK tyrosine kinase. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 61 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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