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Ceftriaxone sodium hydrate

🥰Excellent
Catalog No. T1223Cas No. 104376-79-6
Alias Ceftriaxone Sodium Trihydrate, Ceftriaxone disodium hemiheptahydrate

Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.

Ceftriaxone sodium hydrate
Other Forms of Ceftriaxone sodium hydrate:

Ceftriaxone sodium hydrate

🥰Excellent
Purity: 99.78%
Catalog No. T1223Alias Ceftriaxone Sodium Trihydrate, Ceftriaxone disodium hemiheptahydrateCas No. 104376-79-6
Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
50 mg$30In StockIn Stock
100 mg$41In StockIn Stock
200 mg$59In StockIn Stock
500 mg$97In StockIn Stock
1 mL x 10 mM (in DMSO)$39In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.78%
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Product Introduction

Bioactivity
Description
Ceftriaxone sodium hydrate is a broad-spectrum cephalosporin antibiotic with a very long half-life and high penetrability to meninges, eyes and inner ears.
In vivo
Ceftriaxone maintains stability against β-lactamase enzymes produced by many bacteria, yet the β-lactamases from B. fragilis, some Klebsiella species, P. vulgaris, and P. aeruginosa can deactivate it. Ceftriaxone sodium trihydrate exhibits broad-spectrum in vitro activity against both Gram-positive and Gram-negative bacteria, aerobes, and certain anaerobes. It is effective against Staphylococcus aureus strains, whether penicillin-sensitive or penicillin-resistant (MIC90, 2 to 8 mg/L). However, its efficacy is compromised against strains resistant to methicillin or oxacillin.
SynonymsCeftriaxone Sodium Trihydrate, Ceftriaxone disodium hemiheptahydrate
Chemical Properties
Molecular Weight661.6
FormulaC18H16N8Na2O7S3·3.5H2O
Cas No.104376-79-6
Smiles[Na+].[Na+].[Na+].[Na+].O.O.O.O.O.O.O.Nc1scc(n1)\C(=N\OC)C(=O)N[C@@H]3C(=O)N4C(C([O-])=O)=C(CSC2=NC(=O)C([O-])=NN2C)CS[C@H]34.Nc1scc(n1)\C(=N\OC)C(=O)N[C@@H]3C(=O)N4C(=C(CSC2=NC(=O)C([O-])=NN2C)CS[C@H]34)C([O-])=O
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 145 mg/mL (219.17 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.5115 mL7.5574 mL15.1149 mL75.5744 mL
5 mM0.3023 mL1.5115 mL3.0230 mL15.1149 mL
10 mM0.1511 mL0.7557 mL1.5115 mL7.5574 mL
20 mM0.0756 mL0.3779 mL0.7557 mL3.7787 mL
50 mM0.0302 mL0.1511 mL0.3023 mL1.5115 mL
100 mM0.0151 mL0.0756 mL0.1511 mL0.7557 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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Keywords

third-generationdamagescephalosporinBacterialAntibiotic
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