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Anti-IL-12A Antibody (7K747)

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Catalog No. TMAY-00086
Alias interleukin 12A

Anti-IL-12A Antibody (7K747) is a Mouse antibody targeting IL-12A. Anti-IL-12A Antibody (7K747) can be used in ELISA.

Anti-IL-12A Antibody (7K747)

Anti-IL-12A Antibody (7K747)

😃Good
Catalog No. TMAY-00086Alias interleukin 12A
Anti-IL-12A Antibody (7K747) is a Mouse antibody targeting IL-12A. Anti-IL-12A Antibody (7K747) can be used in ELISA.
Pack SizePriceAvailabilityQuantity
20 μL$69 7-10 days
100 μL$198 7-10 days
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Product Introduction

Bioactivity
Description
Anti-IL-12A Antibody (7K747) is a Mouse antibody targeting IL-12A. Anti-IL-12A Antibody (7K747) can be used in ELISA.
Aliasinterleukin 12A
Ig Type
Monoclonal Mouse IgG1
Clone
7K747
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL12A / IL-12A (rh IL12A / IL-12A; TMPY-01409; P29459; Met 1-Ser 219). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundInterleukin-12 subunit alpha (IL12A/IL-12p35) is also known as Cytotoxic lymphocyte maturation factor 35 kDa subunit, cytotoxic lymphocyte maturation factor 1, p35, NK cell stimulatory factor chain 1, and interleukin-12 alpha chain. IL12A/IL-12p35 is a subunit of a cytokine that acts on T and natural killer cells and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit encoded by this gene, and a 40-kD subunit that is a member of the cytokine receptor family. IL12A/IL-12p35 is required for the T-cell-independent induction of interferon (IFN)-gamma and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity. In clinical, IL-12 remains a very promising immunotherapeutic agent because recent cancer vaccination studies in animal models and humans have demonstrated its powerful adjuvant properties. The immune-modulating characteristics of IL-12 considered responsible for the adjuvant effects, as well as the results of animal and human cancer vaccination studies with IL-12, applied as an adjuvant. IL12A/IL-12p35 indicates a cytokine that is important in the development of prostate cancer.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human IL12A / IL-12A protein (TMPY-01409)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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