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Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636)
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Catalog No. TMAY-02855
Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) is a Rabbit antibody targeting Enterohemorrhagic E. coli (EHEC) stx2B. Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) can be used in ELISA.
Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636)
Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636)
😃Good
Catalog No. TMAY-02855
Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) is a Rabbit antibody targeting Enterohemorrhagic E. coli (EHEC) stx2B. Anti-Enterohemorrhagic E. coli (EHEC) stx2B Antibody (6H636) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $268 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Rabbit Monoclonal Application: ELISA Reactivity: E. coli |
| Ig Type | Rabbit IgG |
| Clone | 6H636 |
| Reactivity | E. coli |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Enterohemorrhagic E. coli (EHEC) stx2B (TMPY-02447; Q93EY4; Met1-Asp89). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | E. Coli STX2B is a subunit of Stx2. Stx2, together with Stx1, formed a family of related toxins which are known as shiga toxins. Shiga toxins are mainly produced by the bacteria S. dysenteriae and the Shigatoxigenic group of Escherichia coli, which includes serotypes O157:H7, O104:H4, and other enterohemorrhagic E. coli (EHEC). A total of 3222 outbreak cases (including 39 deaths) have been reported in northern Germany in May through June 2011. The outbreak strain was typed as an enteroaggregative Shiga-toxin–producing E. coli O104:H4, producing extended-spectrum beta-lactamase. The toxin has two subunits—A and B. E. Coli STX2B is the B subunit. It is a pentamer that binds to specific glycolipids on the host cell, specifically globotriaosylceramide. Following this, the A subunit is internalised and cleaved into two parts. Stx2 has been found to be approximately 400 times more toxic (as quantified by LD50 in mice) than Stx-1. The Stx1 and Stx2 B subunits form a pentameric structure that binds to globotriaosylceramide receptors on eukaryotic cells and promotes endocytosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Enterohemorrhagic E. coli (EHEC) stx2B Protein (TMPY-02447) |
| Antigen Species | E. coli |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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