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MAS825

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Catalog No. T9901A-807

MAS825 is a bispecific monoclonal antibody targeting IL-1β and IL-18, designed to reduce inflammasome-mediated inflammation. This compound combines the inhibitory domains of anti-IL-1β and anti-IL-18 monoclonal antibodies (mAb) into one high-affinity cytokine-capturing bispecific molecule.

MAS825

MAS825

😃Good
Catalog No. T9901A-807
MAS825 is a bispecific monoclonal antibody targeting IL-1β and IL-18, designed to reduce inflammasome-mediated inflammation. This compound combines the inhibitory domains of anti-IL-1β and anti-IL-18 monoclonal antibodies (mAb) into one high-affinity cytokine-capturing bispecific molecule.
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Instruction Manual of Inhibitory Antibody
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
MAS825 is a bispecific monoclonal antibody targeting IL-1β and IL-18, designed to reduce inflammasome-mediated inflammation. This compound combines the inhibitory domains of anti-IL-1β and anti-IL-18 monoclonal antibodies (mAb) into one high-affinity cytokine-capturing bispecific molecule.
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Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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2 Enter the in vivo formulation:
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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