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Brodalumab (AMG 827) is a human monoclonal antibody targeting interleukin 17 receptor (IL-17R) IgG2, often used as an immunosuppressant in the treatment of psoriasis and psoriasis.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 155.00 | |
5 mg | In stock | $ 397.00 | |
10 mg | In stock | $ 582.00 | |
25 mg | In stock | $ 933.00 | |
50 mg | In stock | $ 1,270.00 |
Description | Brodalumab (AMG 827) is a human monoclonal antibody targeting interleukin 17 receptor (IL-17R) IgG2, often used as an immunosuppressant in the treatment of psoriasis and psoriasis. |
In vitro |
Brodalumab (AMG 827) blocks the biological activity of the IL-17A, IL-17F, and IL-17A/F heterodimer signaling pathways by binding to the IL-17RA/RC complex. Additionally, it inhibits the biological activity of the IL-25 (IL-17E) signaling pathway by binding to the IL-17RA/RB complex[1]. Brodalumab is capable of suppressing the inflammatory processes associated with psoriasis[1]. |
Synonyms | LP 0160, KHK-4827, AMG-827 |
Molecular Weight | N/A |
CAS No. | 1174395-19-7 |
store at low temperature
store at -20°C
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Brodalumab 1174395-19-7 Immunology/Inflammation IL Receptor LP 0160 KHK-4827 AMG-827 inhibitor inhibit