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Brodalumab (Synonyms: LP 0160, KHK-4827, AMG-827)
Catalog No. T76779 Copy Product Info
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Brodalumab (AMG 827) is a human monoclonal IgG2 antibody targeting the interleukin 17 receptor (IL-17R), commonly used as an immunosuppressant in treating psoriasis.
Brodalumab
Copy Product Info🥰Excellent
Catalog No. T76779
Synonyms LP 0160, KHK-4827, AMG-827
Brodalumab (AMG 827) is a human monoclonal IgG2 antibody targeting the interleukin 17 receptor (IL-17R), commonly used as an immunosuppressant in treating psoriasis.
Cas No. 1174395-19-7
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $155 | In Stock | In Stock | |
| 5 mg | $397 | In Stock | In Stock | |
| 10 mg | $582 | - | In Stock | |
| 25 mg | $933 | - | In Stock | |
| 50 mg | $1,270 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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With extensive experience in compound synthesis, we can provide rapid custom synthesis services for this product according to your research needs.
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Purity:> 98.3% (SDS-PAGE); 98.4% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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| Description | Brodalumab (AMG 827) is a human monoclonal IgG2 antibody targeting the interleukin 17 receptor (IL-17R), commonly used as an immunosuppressant in treating psoriasis. |
| In vitro | Brodalumab (AMG 827) blocks the biological activity of the IL-17A, IL-17F, and IL-17A/F heterodimer signaling pathways by binding to the IL-17RA/RC complex. Additionally, it inhibits the biological activity of the IL-25 (IL-17E) signaling pathway by binding to the IL-17RA/RB complex[1]. Brodalumab is capable of suppressing the inflammatory processes associated with psoriasis[1]. |
| Synonyms | LP 0160, KHK-4827, AMG-827 |
| Reactivity | Human |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | IL-17Ra/CD217 |
| Molecular Weight | 144.06 kDa |
| Cas No. | 1174395-19-7 |
| Isotype | Human IgG2 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature | Shipping with blue ice/Shipping at ambient temperature. |
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