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VB1-050 is a highly specialized fully human monoclonal antibody target the human solute carrier family 2 member 8 protein, also known as glucose transporter 8 or GLUT8, inhibition of hexose transport and receptor-mediated internalization across various preclinical experimental models of breast, liver, prostate, and colon cancers where the target antigen exhibits preferential expression compared to limited reactivity in normal tissues.

| Description | VB1-050 is a highly specialized fully human monoclonal antibody target the human solute carrier family 2 member 8 protein, also known as glucose transporter 8 or GLUT8, inhibition of hexose transport and receptor-mediated internalization across various preclinical experimental models of breast, liver, prostate, and colon cancers where the target antigen exhibits preferential expression compared to limited reactivity in normal tissues. |
| In vitro | In binding assays and immunohistochemical screens, VB1-050 demonstrated high specificity for Glucose Transporter-8 (Glut-8) in multiple human cancer cell lines and primary tumor tissues [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | SLC2A8 |
| Isotype | IgG1 |
| Storage | store at low temperature | -20°C for 2 years, 4°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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