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Anti-IL-28B Antibody (4X585) (Synonyms: interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B)
Catalog No. TMAY-02136 Copy Product Info
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Anti-IL-28B Antibody (4X585) is a Mouse antibody targeting IL-28B. Anti-IL-28B Antibody (4X585) can be used in ELISA.
Anti-IL-28B Antibody (4X585)
Copy Product Info🥰Excellent
Catalog No. TMAY-02136
Synonyms interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B
Anti-IL-28B Antibody (4X585) is a Mouse antibody targeting IL-28B. Anti-IL-28B Antibody (4X585) can be used in ELISA.
Anti-IL-28B Antibody
(4X585)
(4X585)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-IL-28B Antibody (4X585) is a Mouse antibody targeting IL-28B. Anti-IL-28B Antibody (4X585) can be used in ELISA. |
| Synonyms | interferon, λ3, interferon, lambda 3, IL28C, IL-28B, IL28B |
| Ig Type | Mouse IgG2b |
| Clone | 4X585 |
| Reactivity | Human |
| Specificity | Human IL-28B/Interferon lambda-3 |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-28B/IFN-lambda-3 (rh IL-28B/IFN-lambda-3; TMPY-01872; NP_742151.2; Met1-Val196). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-28B (IL-28B) also known as Interferon lambda-3 and IFN-lambda-3, belongs to the type III interferon family of cytokines and are highly similar to IL-29. IL-28B belongs to the newly described interferon lambda (IFNλ) family of cytokines. IL-28B is a cytokine with immunomodulatory activity. It functions in Up-regulating MHC class I antigen expression. IL-28B displays potent antiviral activity and antitumor activity. This cytokine serves as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway. IL-28B, like IL-12, is capable of robustly enhancing adaptive immunity. Moreover, we describe for the first time how IL-28B reduces regulatory T-cell populations during DNA vaccination, whereas IL-12 increases this cellular subset. We also show that IL-28B, unlike IL-12, can increase the percentage of splenic CD8+ T cells in vaccinated animals and that these cells are more granular and have higher antigen-specific cytolytic degranulation compared with cells taken from animals that received IL-12 as an adjuvant. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human IL-28B/IFN-lambda-3 Protein (TMPY-01872) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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