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Anti-CES3/Carboxylesterase 3 Antibody (5Z251)

🥰Excellent
Catalog No. TMAY-01667

Anti-CES3/Carboxylesterase 3 Antibody (5Z251) is a Mouse antibody targeting CES3/Carboxylesterase 3. Anti-CES3/Carboxylesterase 3 Antibody (5Z251) can be used in ELISA.

Anti-CES3/Carboxylesterase 3 Antibody (5Z251)

Anti-CES3/Carboxylesterase 3 Antibody (5Z251)

🥰Excellent
Catalog No. TMAY-01667
Anti-CES3/Carboxylesterase 3 Antibody (5Z251) is a Mouse antibody targeting CES3/Carboxylesterase 3. Anti-CES3/Carboxylesterase 3 Antibody (5Z251) can be used in ELISA.
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Product Introduction

Bioactivity
Description
Anti-CES3/Carboxylesterase 3 Antibody (5Z251) is a Mouse antibody targeting CES3/Carboxylesterase 3. Anti-CES3/Carboxylesterase 3 Antibody (5Z251) can be used in ELISA.
Ig Type
Monoclonal Mouse IgG2b
Clone
5Z251
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CES3 / Carboxylesterase 3 (rh CES3 / Carboxylesterase 3; NP_079198.2Met 1-Glu 561). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundCarboxylesterases hydrolyze esters of short-chain fatty acids and have roles in animals ranging from signal transduction to xenobiotic detoxification. In enzymology, a carboxylesterase is an enzyme that catalyzes the chemical reaction: a carboxylic ester + H2O = an alcohol + a carboxylate. Most enzymes from this group belong to the superfamily of hydrolases with alpha/beta protein fold (so called Alpha/beta hydrolase fold), specifically those acting on carboxylic ester bonds. The carboxylesterase family of evolutionarily related proteins (those with clear sequence homology to each other) includes a number of proteins with different substrate specificities, such as acetylcholinesterases. Carboxylesterase 3, also known as Liver carboxylesterase 31 homolog and CES3, is a endoplasmic reticulum lumen which belongs to thetype-B carboxylesterase/lipase family. CES3 is involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. CES3 shows low catalytic efficiency for hydrolysis of CPT-11, a prodrug for camptothecin used in cancer therapeutics. CES3 is expressed in liver, colon and small intestine.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human CES3 / Carboxylesterase 3 protein
Antigen Species
Human
Biology Area
Serine Proteases and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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