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Oxacillin

Name: Oxacillin
Brand: TargetMol
SKU: T61951
Price: 293 USD
Availability: InStock
Rating: 5 (10 reviews)

(Synonyms: Oxabel) Copy Product Info

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Synonyms: Oxabel

Catalog No. T61951 Copy Product Info

Purity: 98.52%

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Oxacillin (Oxabel) is an orally active and antibacterial penicillin antibiotic. It works by inhibiting bacterial cell wall synthesis and exerting bactericidal effects.

Cas No. 66-79-5

Pack Size	Price	USA Stock	Global Stock
1 mg	$293	In Stock	In Stock
5 mg	$722	In Stock	In Stock
10 mg	$987	In Stock	In Stock
25 mg	$1,520	In Stock	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:98.52%

Appearance:Solid

Color:White

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COA HNMR HPLC

Product Introduction

Bioactivity

Description	Oxacillin (Oxabel) is an orally active and antibacterial penicillin antibiotic. It works by inhibiting bacterial cell wall synthesis and exerting bactericidal effects.
In vitro	Oxacillin has extensive inhibition of gram-positive bacteria. The MIC of Oxacillin against Streptococcus A, pneumococcus, sensitive Staphylococcus and penicillin-resistant staphylococcus were 0.05, 0.09, 0.32 and 0.80 μg/mL, respectively.[1]
In vivo	In a mouse model of Staphylococcus aureus Evans infection, Oxacillin was subcutaneously administered with 253.3 mg/kg CD50 and orally administered with 187.2 mg/kg CD50. [2]
Synonyms	Oxabel

Chemical Properties

Molecular Weight	401.44
Formula	C₁₉H₁₉N₃O₅S
Cas No.	66-79-5
Smiles	C(O)(=O)[C@@H]1N2[C@@]([C@H](NC(=O)C=3C(=NOC3C)C4=CC=CC=C4)C2=O)(SC1(C)C)[H]

Storage & Solubility Information

Storage

Keep away from moisture Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 135 mg/mL (336.29 mM)

In Vivo Formulation

10% DMSO+90% Saline: 10 mg/mL (24.91 mM), Suspension.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4910 mL	12.4552 mL	24.9103 mL	124.5516 mL
5 mM	0.4982 mL	2.4910 mL	4.9821 mL	24.9103 mL
10 mM	0.2491 mL	1.2455 mL	2.4910 mL	12.4552 mL
20 mM	0.1246 mL	0.6228 mL	1.2455 mL	6.2276 mL
50 mM	0.0498 mL	0.2491 mL	0.4982 mL	2.4910 mL
100 mM	0.0249 mL	0.1246 mL	0.2491 mL	1.2455 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 µL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 µL Tween 80 and mix well until fully clarified.

3) Add 450 µL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Related Tags: Oxacillin chemical structure | Oxacillin in vivo | Oxacillin in vitro | Oxacillin formula | Oxacillin molecular weight