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Sulfamethazine sodium

Name: Sulfamethazine sodium
Brand: TargetMol
SKU: T2184L
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T2184LCas No. 1981-58-4

Alias Sulfamethazine sodium salt, Sulfadimethyldiazine Sodium Salt

Sulfamethazine sodium (Sulfadimethyldiazine Sodium Salt) salt is a sodium salt form of sulfamethazine, a sulfonamide antibiotic used in the livestock industry.

Sulfamethazine sodium

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Purity: 99.72%

Catalog No. T2184LAlias Sulfamethazine sodium salt, Sulfadimethyldiazine Sodium SaltCas No. 1981-58-4

Sulfamethazine sodium (Sulfadimethyldiazine Sodium Salt) salt is a sodium salt form of sulfamethazine, a sulfonamide antibiotic used in the livestock industry.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 g	$30	-	In Stock
1 mL x 10 mM (in DMSO)	$29	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.72%

Appearance:Solid

Color:White

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COA HNMR HPLC LCMS

Product Introduction

Sulfamethazine sodium AI Summary

Sulfamethazine sodium exhibits diverse bioactivities across several assays. It acts as an inhibitor of AmpC Beta-Lactamase with a potency of 8912.5 nM and shows potential as a treatment for Ataxia-Telangiectasia with a potency of 39810.7 nM. It also inhibits BAZ2B with a potency of 707.9 nM and the malarial parasite plastid, resulting in delayed death with potencies of 14715.7 nM and 18526.0 nM depending on the incubation period. Additionally, it inhibits Polymerase Iota and Polymerase Kappa with potencies of 89125.1 nM each and demonstrates antiviral activity against the Foot and Mouth Disease Virus with a potency of 10000.0 nM. Moreover, it has shown low activity in inhibiting the cell viability of Vero E6 cells infected with SARS-CoV-2 (BavPat1 strain) at a low MOI after 72 hours, indicated by an inhibition index of 0.07695..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description	Sulfamethazine sodium (Sulfadimethyldiazine Sodium Salt) salt is a sodium salt form of sulfamethazine, a sulfonamide antibiotic used in the livestock industry.
Synonyms	Sulfamethazine sodium salt, Sulfadimethyldiazine Sodium Salt

Chemical Properties

Molecular Weight	300.31
Formula	C₁₂H₁₃N₄NaO₂S
Cas No.	1981-58-4
Smiles	S(=O)(=O)([N-]c1nc(cc(n1)C)C)c1ccc(N)cc1.[Na+]
Relative Density.	1.392g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (183.14 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Corn Oil: 2.5 mg/mL (8.32 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.3299 mL	16.6495 mL	33.2989 mL	166.4946 mL
5 mM	0.6660 mL	3.3299 mL	6.6598 mL	33.2989 mL
10 mM	0.3330 mL	1.6649 mL	3.3299 mL	16.6495 mL
20 mM	0.1665 mL	0.8325 mL	1.6649 mL	8.3247 mL
50 mM	0.0666 mL	0.3330 mL	0.6660 mL	3.3299 mL
100 mM	0.0333 mL	0.1665 mL	0.3330 mL	1.6649 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc