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Anti-IL-6 Antibody (5B904) is a Rabbit antibody targeting IL-6. Anti-IL-6 Antibody (5B904) can be used in ELISA.
Description | Anti-IL-6 Antibody (5B904) is a Rabbit antibody targeting IL-6. Anti-IL-6 Antibody (5B904) can be used in ELISA. |
Ig Type | Monoclonal Rabbit IgG |
Clone | 5B904 |
Reactivity | Rat |
Application | ELISA |
Recommended Dose | ELISA: 1:5000-1:10000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Rat IL-6 (rR IL-6; TMPY-03298; NP_036721.1; Phe25-Thr211). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | Unconjugated |
Immunogen | Recombinant Rat IL-6 Protein (TMPY-03298) |
Antigen Species | Rat |
Biology Area | Neuroinflammation, Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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