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Anti-IL-17RA Antibody (7D356)
😃Good
Catalog No. TMAY-03765
Alias interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Anti-IL-17RA Antibody (7D356) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (7D356) can be used in ELISA.
Anti-IL-17RA Antibody (7D356)
Anti-IL-17RA Antibody (7D356)
😃Good
Catalog No. TMAY-03765Alias interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Anti-IL-17RA Antibody (7D356) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (7D356) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $198 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-IL-17RA Antibody (7D356) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (7D356) can be used in ELISA. |
| Alias | interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5 |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 7D356 |
| Reactivity | Rat |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Rat IL-17R / IL-17RA （CD217） (TMPY-02996; NP_001101353.2; Met1-Pro320). The IgG fraction of the cell culture supernatant was purified by Protein A affinity. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Rat IL-17R / IL-17RA （CD217） protein (TMPY-02996) |
| Antigen Species | Rat |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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