Shopping Cart

Remove All

Your shopping cart is currently empty

Proceed to checkout Continue shopping

Anti-IL-18 Antibody (4N26) (Synonyms: interleukin 18, IL-1g, IL1F4, IL-18, IGIF)

Name: Anti-IL-18 Antibody (4N26)
Brand: TargetMol
SKU: TMAY-03077
Rating: 4.5 (1 reviews)

Catalog No. TMAY-03077 Copy Product Info

🥰Excellent

Anti-IL-18 Antibody (4N26) is a Rabbit antibody targeting IL-18. Anti-IL-18 Antibody (4N26) can be used in ELISA,ELISA(Det).

Anti-IL-18 Antibody (4N26)

Copy Product Info

🥰Excellent

Catalog No. TMAY-03077

Synonyms interleukin 18, IL-1g, IL1F4, IL-18, IGIF

Anti-IL-18 Antibody (4N26) is a Rabbit antibody targeting IL-18. Anti-IL-18 Antibody (4N26) can be used in ELISA,ELISA(Det).

Anti-IL-18 Antibody
(4N26)

Pack Size	Price	USA Stock	Global Stock	Quantity
20 μL	$92	7-10 days	7-10 days
100 μL	$270	7-10 days	7-10 days

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

Add to Cart

Add to Quotation

For research use only—not for human use. No sales to individuals. Use as intended only.

Questions

Resource Download

Instruction Manual of Detection Antibody

Product Introduction

Bioactivity

Description	Anti-IL-18 Antibody (4N26) is a Rabbit antibody targeting IL-18. Anti-IL-18 Antibody (4N26) can be used in ELISA,ELISA(Det).
Synonyms	interleukin 18, IL-1g, IL1F4, IL-18, IGIF
Ig Type	Rabbit IgG
Clone	4N26
Reactivity	Mouse
Specificity	Mouse IL-18 No cross-reactivity in ELISA with Human IL1F7 Human IL1F9
Application	ELISA ELISA(Det)
Recommended Dose	ELISA: 1:5000-1:10000; ELISA(Det): 1:1000-1:10000
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL-18 (rM IL-18; P70380Asn36-Ser192).
Purification	Protein A
Appearance	Liquid
Formulation	0.2 μm filtered solution in PBS
Research Background	Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of IL-18 and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. IL-18 is an IL-1-like cytokine that requires cleavage with caspase-1 to become active, was found to increase IgE production in a CD4+ T cell -, IL-4- and STAT6-dependent fashion. IL-18 and T cell receptor-mediated stimulation could induce naive CD4+ T cells to develop into IL-4-producing cells in vitro. Thus, caspase-1 and IL-18 may be critical in the regulation of IgE production in vivo, providing a potential therapeutic target for allergic disorders. IL-18 production in primary synovial cultures and purified synovial fibroblasts was, in turn, upregulated by TNF-α and IL-1β, suggesting that monokine expression can feedback to promote Th1 cell development in the synovial membrane. Besides, synergistic combinations of IL-18, IL-12, and IL-15 may be of importance in sustaining both Th1 responses and monokine production in RA.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy

Related Conjugates and Formulations

Conjucates	Unconjugated
Others Formats	HRP
Antibody Types Available	2

Antigen Details

Immunogen	Recombinant Protein: Mouse IL-18 protein
Antigen Species	Mouse
Biology Area	Neuroinflammation

Chemical Properties

Stability & Storage

Stability & Storage	Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
Transport	Shipping with blue ice.

Calculator

Dilution Calculator
Reconstitution Calculator

Keywords

IL18IL 18

Related Tags: buy Anti-IL-18 Antibody (4N26) | purchase Anti-IL-18 Antibody (4N26) | Anti-IL-18 Antibody (4N26) cost | order Anti-IL-18 Antibody (4N26)