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Anti-IL-6 Antibody-Biotin (9W140) is a Biotin-conjugated Mouse antibody targeting IL-6. Anti-IL-6 Antibody-Biotin (9W140) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μg | $93 | 7-10 days | |
100 μg | $292 | 7-10 days |
Description | Anti-IL-6 Antibody-Biotin (9W140) is a Biotin-conjugated Mouse antibody targeting IL-6. Anti-IL-6 Antibody-Biotin (9W140) can be used in ELISA. |
Alias | interleukin 6 |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 9W140 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 0.1-1 μg/ml |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL-6 / Interleukin-6 (rh IL-6 / Interleukin-6; TMPY-00863; NP_000591.1; Val30-Met212). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and then biotinylated. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Interleukin-6 (IL-6) is a multifunctional α-helical cytokine that regulates cell growth and differentiation of various tissues, which is known particularly for its role in the immune response and acute phase reactions. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as a phosphorylated and variably glycosylated molecule. It exerts actions through its heterodimeric receptor composed of IL-6R that lacks the tyrosine/kinase domain and binds IL-6 with low affinity, and ubiquitously expressed glycoprotein 130 (gp130) that binds the IL-6. IL-6R complex with high affinity and thus transduces signals. IL-6 is also involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined as an essential role in directing the transition from innate to acquired immunity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | Biotin |
Others Formats | Unconjugated/HRP |
Antibody Types Available | 3 |
Immunogen | Recombinant Human IL-6 / Interleukin-6 Protein (TMPY-00863) |
Antigen Species | Human |
Biology Area | Neuroinflammation, Cancer Drug Targets |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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