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Hidrosmin
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Catalog No. T210010Cas No. 115960-14-0
Hidrosmin is a flavonoid compound and a derivative of Diosmin. It offers beneficial effects on diabetic nephropathy (DN) by reducing inflammation, oxidative stress, and aging pathways. Hidrosmin is applicable in research concerning venous insufficiency and diabetes.
Hidrosmin
🥰Excellent
Catalog No. T210010Cas No. 115960-14-0
Hidrosmin is a flavonoid compound and a derivative of Diosmin. It offers beneficial effects on diabetic nephropathy (DN) by reducing inflammation, oxidative stress, and aging pathways. Hidrosmin is applicable in research concerning venous insufficiency and diabetes.
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Product Introduction
Bioactivity
Chemical Properties
| Description | Hidrosmin is a flavonoid compound and a derivative of Diosmin. It offers beneficial effects on diabetic nephropathy (DN) by reducing inflammation, oxidative stress, and aging pathways. Hidrosmin is applicable in research concerning venous insufficiency and diabetes. |
| In vitro | Hidrosmin (0.1-1 mM) reduces cytokine expression in kidney cells exposed to high glucose and/or inflammatory conditions and regulates redox balance genes. |
| In vivo | Hidrosmin (300 mg/kg, administered orally via feeding once daily for 7 weeks) can ameliorate kidney damage in diabetic mice. |
| Molecular Weight | O(CCO)C1=C2C(OC(=CC2=O)C3=CC(O)=C(OC)C=C3)=CC(O[C@@H]4O[C@H](CO[C@H]5[C@H](O)[C@H](O)[C@@H](O)[C@H](C)O5)[C@@H](O)[C@H](O)[C@H]4O)=C1 |
| Formula | C30H36O16 |
| Cas No. | 115960-14-0 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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