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Anti-ICAM-2/CD102 Antibody (8F386)

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Catalog No. TMAY-00625
Alias Ly-60, intercellular adhesion molecule 2, Icam-2, CD102

Anti-ICAM-2/CD102 Antibody (8F386) is a Rabbit antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (8F386) can be used in ELISA.

Anti-ICAM-2/CD102 Antibody (8F386)

Anti-ICAM-2/CD102 Antibody (8F386)

😃Good
Catalog No. TMAY-00625Alias Ly-60, intercellular adhesion molecule 2, Icam-2, CD102
Anti-ICAM-2/CD102 Antibody (8F386) is a Rabbit antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (8F386) can be used in ELISA.
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100 μL$269 7-10 days
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Product Introduction

Bioactivity
Description
Anti-ICAM-2/CD102 Antibody (8F386) is a Rabbit antibody targeting ICAM-2/CD102. Anti-ICAM-2/CD102 Antibody (8F386) can be used in ELISA.
AliasLy-60, intercellular adhesion molecule 2, Icam-2, CD102
Ig Type
Monoclonal Rabbit IgG
Clone
8F386
Reactivity
Human
Verified Activity
Anti-ICAM2 rabbit monoclonal antibody at 1:500 dilution.

-Lane A: HL-60 Whole Cell lysate.

-Lysates/proteins at 30 μg per lane.

-Secondary

-Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.

-Developed using the Odyssey technique.

-Performed under reducing conditions.

-Predicted band size:32 kDa.

-Observed band size:41 kDa
Application
ELISA
Recommended Dose
ELISA: 1:5000-1:10000
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Human ICAM2 (rh ICAM2; TMPY-01418; NP_000864.2; Met 1-Gln 223).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIntercellular adhesion molecule 2 (ICAM-2, CD102), belongs to the ICAM family consisting of three members identified as ligands for integrin receptors. It is a type I transmembrane glycoprotein with two Ig-like C2-type domains and binds to the leukocyte integrins LFA-1 (CD11a/CD18) and Mac-1 (CD11b/CD18). As the second ligand of leukocyte function-associated antigen-1, ICAM-2 functions as a costimulatory molecule for effector cells. ICAM-2 is mainly expressed on vascular endothelial and hematopoietic cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocyte with other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity, and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relationship with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in the diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human ICAM2 protein (TMPY-01418)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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