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Fenoterol hydrobromide

Name: Fenoterol hydrobromide
Brand: TargetMol
SKU: T22331
Price: 29 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T22331Cas No. 1944-12-3

Fenoterol hydrobromide is an orally active and selective β2-adrenoceptor agonist and bronchodilator used in the study of cardiovascular diseases such as asthma and bronchitis.

Fenoterol hydrobromide

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Purity: 99.88%

Catalog No. T22331Cas No. 1944-12-3

Fenoterol hydrobromide is an orally active and selective β2-adrenoceptor agonist and bronchodilator used in the study of cardiovascular diseases such as asthma and bronchitis.

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
10 mg	$29	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$74	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.88%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Fenoterol hydrobromide is an orally active and selective β2-adrenoceptor agonist and bronchodilator used in the study of cardiovascular diseases such as asthma and bronchitis.
In vitro	Fenoterol hydrobromide inhibited lipopolysaccharide (LPS)-induced AMPK activation and inflammatory cytokine production in THP-1 cells. Fenoterol hydrobromide treatment reduced AICAR-induced AMPK activation, NF-κB activation and TNF-α release, and also significantly down-regulated the elevated phosphorylation level of AMPK. [1] Fenoterol hydrobromide is a potent activator of exosome biogenesis and/or secretion in PC cells. [2]
In vivo	0.7 mg/kg Fenoterol hydrobromide injected intraperitoneally twice daily was treated to suppress mechanically abnormal pain during chronic treatment. [3]

Chemical Properties

Molecular Weight	384.27
Formula	C₁₇H₂₂BrNO₄
Cas No.	1944-12-3
Smiles	Br.OC1=CC=C(C=C1)CC(NCC(O)C=2C=C(O)C=C(O)C2)C
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 20 mg/mL (52.05 mM), Sonication is recommended.

DMSO: 80 mg/mL (208.19 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 3.3 mg/mL (8.59 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

H2O/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6023 mL	13.0117 mL	26.0234 mL	130.1168 mL
5 mM	0.5205 mL	2.6023 mL	5.2047 mL	26.0234 mL
10 mM	0.2602 mL	1.3012 mL	2.6023 mL	13.0117 mL
20 mM	0.1301 mL	0.6506 mL	1.3012 mL	6.5058 mL
50 mM	0.0520 mL	0.2602 mL	0.5205 mL	2.6023 mL

DMSO

	1mg	5mg	10mg	50mg
100 mM	0.0260 mL	0.1301 mL	0.2602 mL	1.3012 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc