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Anti-MRSA agent 32

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Catalog No. T211983

Anti-MRSA agent 32 (Compound 26) is an orally active selective activator of the Staphylococcus aureus ClpP protease (SaClpP) with an EC50 of 0.98 μM. By activating the SaClpP protease, it causes the abnormal degradation of bacterial proteins and inhibits the proliferation of Staphylococcus aureus. In a mouse skin infection model, Anti-MRSA agent 32 promotes wound healing. This compound holds potential for research in methicillin-resistant Staphylococcus aureus (MRSA) and other infectious diseases.

Anti-MRSA agent 32

Anti-MRSA agent 32

😃Good
Catalog No. T211983
Anti-MRSA agent 32 (Compound 26) is an orally active selective activator of the Staphylococcus aureus ClpP protease (SaClpP) with an EC50 of 0.98 μM. By activating the SaClpP protease, it causes the abnormal degradation of bacterial proteins and inhibits the proliferation of Staphylococcus aureus. In a mouse skin infection model, Anti-MRSA agent 32 promotes wound healing. This compound holds potential for research in methicillin-resistant Staphylococcus aureus (MRSA) and other infectious diseases.
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Description
Anti-MRSA agent 32 (Compound 26) is an orally active selective activator of the Staphylococcus aureus ClpP protease (SaClpP) with an EC50 of 0.98 μM. By activating the SaClpP protease, it causes the abnormal degradation of bacterial proteins and inhibits the proliferation of Staphylococcus aureus. In a mouse skin infection model, Anti-MRSA agent 32 promotes wound healing. This compound holds potential for research in methicillin-resistant Staphylococcus aureus (MRSA) and other infectious diseases.
Chemical Properties
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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