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DRX-065

Name: DRX-065
Brand: TargetMol
SKU: T27210
Rating: 4.5 (1 reviews)

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Catalog No. T27210Cas No. 1259828-75-5

Alias DRX065, DRX 065, deuterated R-enantiomer of pioglitazone

DRX-065 is a stabilized and deuterated R-enantiomer of pioglitazone. DRX-065 has pharmacological properties desirable for the treatment of NASH (mitochondrial function modulation, non-steroidal anti-inflammatory effects, and glucose lowering effects) without the undesired PPARγ-related weight gain side effect.

DRX-065

😃Good

Catalog No. T27210Alias DRX065, DRX 065, deuterated R-enantiomer of pioglitazoneCas No. 1259828-75-5

Pack Size	Price	Availability
1 mg	$698	10-14 weeks
5 mg	$1,470	10-14 weeks
10 mg	$1,990	10-14 weeks
25 mg	$2,950	10-14 weeks
50 mg	$3,980	10-14 weeks
100 mg	$5,378	10-14 weeks

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Product Introduction

Bioactivity

Description	DRX-065 is a stabilized and deuterated R-enantiomer of pioglitazone. DRX-065 has pharmacological properties desirable for the treatment of NASH (mitochondrial function modulation, non-steroidal anti-inflammatory effects, and glucose lowering effects) without the undesired PPARγ-related weight gain side effect.
Synonyms	DRX065, DRX 065, deuterated R-enantiomer of pioglitazone

Chemical Properties

Molecular Weight	357.45
Formula	C₁₉H₂₀N₂O₃S
Cas No.	1259828-75-5
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

DRX-065