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RT2

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Catalog No. TP3706Cas No. 1539295-33-4

RT2 is a cationic amphiphilic antimicrobial peptide rich in tryptophan that primarily targets lipopolysaccharides (LPS) on bacterial surfaces and intracellular DNA. By binding to surface LPS, RT2 interacts with cytoplasmic membrane phospholipids, enabling rapid penetration of the bacterial cell membrane and subsequent binding to cytoplasmic components such as DNA, exerting its antibacterial effects. RT2 holds potential for research into acute and chronic infections caused by planktonic bacteria.

RT2

RT2

😃Good
Catalog No. TP3706Cas No. 1539295-33-4
RT2 is a cationic amphiphilic antimicrobial peptide rich in tryptophan that primarily targets lipopolysaccharides (LPS) on bacterial surfaces and intracellular DNA. By binding to surface LPS, RT2 interacts with cytoplasmic membrane phospholipids, enabling rapid penetration of the bacterial cell membrane and subsequent binding to cytoplasmic components such as DNA, exerting its antibacterial effects. RT2 holds potential for research into acute and chronic infections caused by planktonic bacteria.
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction

Bioactivity
Description
RT2 is a cationic amphiphilic antimicrobial peptide rich in tryptophan that primarily targets lipopolysaccharides (LPS) on bacterial surfaces and intracellular DNA. By binding to surface LPS, RT2 interacts with cytoplasmic membrane phospholipids, enabling rapid penetration of the bacterial cell membrane and subsequent binding to cytoplasmic components such as DNA, exerting its antibacterial effects. RT2 holds potential for research into acute and chronic infections caused by planktonic bacteria.
Chemical Properties
Molecular Weight2545.91
FormulaC126H165N39O20
Cas No.1539295-33-4
SmilesC([C@@H](C(N[C@@H](CC=1C=2C(NC1)=CC=CC2)C(N[C@H](C(N[C@H](C(N[C@@H](CC=3C=4C(NC3)=CC=CC4)C(N[C@@H](CC=5C=6C(NC5)=CC=CC6)C(N)=O)=O)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=O)NC([C@@H](NC([C@H](CC=7C=8C(NC7)=CC=CC8)NC([C@H](CC=9C=%10C(NC9)=CC=CC%10)NC([C@@H](NC([C@H](CC%11=CC=C(O)C=C%11)NC([C@@H](NC(=O)[C@H]%12N(C([C@@H](NC([C@@H](NC(CNC([C@H](CC(N)=O)N)=O)=O)C(C)C)=O)CCC(N)=O)=O)CCC%12)CCCCN)=O)=O)CCCNC(=N)N)=O)=O)=O)CCCNC(=N)N)=O)C=%13C=%14C(NC%13)=CC=CC%14
Storage & Solubility Information
Storagekeep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
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