Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Chlorhexidine digluconate is a broad-spectrum antiseptic and disinfectant with broad-spectrum antimicrobial activity, inhibits both Gram-positive and Gram-negative bacteria, induces necrosis and apoptosis, and can be used in the study of bacterial infections.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | Inquiry | |
1 g | In stock | Inquiry | |
5 g | In stock | $ 40.00 |
Description | Chlorhexidine digluconate is a broad-spectrum antiseptic and disinfectant with broad-spectrum antimicrobial activity, inhibits both Gram-positive and Gram-negative bacteria, induces necrosis and apoptosis, and can be used in the study of bacterial infections. |
In vitro | Chlorhexidine digluconate exhibits dose-dependent and time-dependent effects on Chinese hamster ovary (CHO) cells (P < 0.05). As the concentration of Chlorhexidine digluconate increases, the mode of cell death shifts from apoptosis to necrosis: Chlorhexidine digluconate (0.00005%, 0.0001%, 0.0005%; 1 hour) induces approximately 1.62%, 5.51%, and 5.47% apoptosis, while the percentages of cell necrosis are 2.38%, 8.62%, and 22.50%, respectively.[1]. |
In vivo | Compared to mice in group D receiving only saline lavage, a single intraperitoneal injection of Chlorhexidine gluconate (0.05%, 0.025%) significantly reduces the incidence of intra-abdominal abscess formation after lavage surgery. There is no significant difference in the incidence of gross adhesions between groups of mice that have or have not undergone surgery[2]. |
Molecular Weight | 897.76 |
Formula | C34H54Cl2N10O14 |
CAS No. | 18472-51-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30 mg/mL (33.42 mM), Sonication is recommended.
H2O: 80 mg/mL (89.11 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Chlorhexidine digluconate 18472-51-0 Apoptosis Microbiology/Virology Antibiotic inhibitor inhibit