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Astegolimab (Synonyms: RG 6149, MSTT 1041A)

Catalog No. T76910 Copy Product Info
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Astegolimab (RG 6149) is a humanised IgG2 monoclonal antibody that targets the IL-33 receptor and inhibits IL-33 signalling. Astegolimab is used in the study of chronic obstructive pulmonary disease (COPD) and severe asthma in adults.

Astegolimab

Copy Product Info
🥰Excellent
Catalog No. T76910
Synonyms RG 6149, MSTT 1041A

Astegolimab (RG 6149) is a humanised IgG2 monoclonal antibody that targets the IL-33 receptor and inhibits IL-33 signalling. Astegolimab is used in the study of chronic obstructive pulmonary disease (COPD) and severe asthma in adults.

Astegolimab
Cas No. 2173054-79-8
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$237-In Stock
5 mg$642-In Stock
10 mg$987-In Stock
25 mg$1,520-In Stock
50 mg$1,980-In Stock
100 mg$2,770-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Astegolimab (RG 6149) is a humanised IgG2 monoclonal antibody that targets the IL-33 receptor and inhibits IL-33 signalling. Astegolimab is used in the study of chronic obstructive pulmonary disease (COPD) and severe asthma in adults.
SynonymsRG 6149, MSTT 1041A
Reactivity
Human
Verified Activity
Immobilized Human ST2/IL-1 RL1 Protein (His) (TMPY-01359) at 1 μg/mL (100 μL/well) can bind Astegolimab. The EC50 is 6.42 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-1RL1/ST2/IL-33R
Chemical Properties
Molecular Weight144.98 kDa
Cas No.2173054-79-8
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
Storage-20°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

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