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Astaxanthin

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Catalog No. T3138Cas No. 472-61-7
Alias β-Carotene-4,4'-dione, trans-Astaxanthin, Ovoester, AstaREAL

Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aquatic organisms. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. It may be found in fish feed or some animal food as a color additive.

Astaxanthin

Astaxanthin

Copy Product Info
🥰Excellent
Purity: 99.79%
Catalog No. T3138Alias β-Carotene-4,4'-dione, trans-Astaxanthin, Ovoester, AstaREALCas No. 472-61-7
Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aquatic organisms. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. It may be found in fish feed or some animal food as a color additive.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
2 mg$30In StockIn Stock
5 mg$43In StockIn Stock
10 mg$61In StockIn Stock
25 mg$98In StockIn Stock
50 mg$133In StockIn Stock
100 mg$196In StockIn Stock
500 mg$487In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.79%
Color:Purple to Black
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Product Introduction

Astaxanthin AI Summary
Astaxanthin exhibits diverse pharmacological activities including antiradical, antiplasmodial, hypoglycemic, antidiabetic, antiviral, and inhibitory effects on specific proteins. It acts as a DPPH radical scavenger with a 52.0% activity at a concentration of 1500 µM. It shows antiplasmodial activity against Plasmodium falciparum strains W2, 7G8, and GB4 with IC50 values of 7943.28 nM for the W2 and 7G8 strains, and 12589.25 nM for the GB4 strain. In mouse models, at a dosage of 10 mg/kg, it reduces plasma glucose levels, demonstrating hypoglycemic activity by lowering glucose levels by 6.02 mmol/L and 6.14 mmol/L in oral glucose tolerance tests, and antidiabetic activity by reducing glucose levels by 10.11 mmol/L and 13.03 mmol/L in an alloxan-induced diabetic model. Astaxanthin inhibits the activity of OATP1B1 and OATP1B3 in CHO cells with inhibition rates of 95.25% and 87.19% respectively at 10 µM. It also shows antiviral activity by reducing SARS-CoV-2 induced cytotoxicity in Caco-2 cells by approximately 29.9% at a concentration of 10 µM after 48 hours and slightly inhibits SARS-CoV-2 3CL-Pro protease by 17.74% at a concentration of 20 µM. Furthermore, it inhibits the cytotoxicity of SARS-CoV-2 in VERO-6 cells by 2.6% at 10 µM concentration after 48 hours and shows a 10.39% inhibitory activity against human HDAC6 with a commercial peptide substrate, although it does not inhibit with a custom peptide substrate..
Note: Summary generated by AI. Data source: ChEMBL
Bioactivity
Description
Astaxanthin (trans-Astaxanthin) is a keto-carotenoid in the terpenes class of chemical compounds. It is classified as a xanthophyll but it is a carotenoid with no vitamin A activity. It is present in most red-colored aquatic organisms. Astaxanthin has shown to mediate anti-oxidant and anti-inflammatory actions. It may be found in fish feed or some animal food as a color additive.
Synonymsβ-Carotene-4,4'-dione, trans-Astaxanthin, Ovoester, AstaREAL
Chemical Properties
Molecular Weight596.84
FormulaC40H52O4
Cas No.472-61-7
SmilesC\C(\C=C\C=C(/C)\C=C\C1=C(C)C(=O)[C@@H](O)CC1(C)C)=C/C=C/C=C(\C)/C=C/C=C(\C)/C=C/C1=C(C)C(=O)[C@@H](O)CC1(C)C
Relative Density.1.071 g/cm3
Storage & Solubility Information
Storagestore at low temperature,keep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 5.97 mg/mL (10 mM), Sonication is recommended.
DMF: 1 mg/mL (1.68 mM), Sonication is recommended.
Solution Preparation Table
DMF/DMSO
1mg5mg10mg50mg
1 mM1.6755 mL8.3775 mL16.7549 mL83.7745 mL
DMSO
1mg5mg10mg50mg
5 mM0.3351 mL1.6755 mL3.3510 mL16.7549 mL
10 mM0.1675 mL0.8377 mL1.6755 mL8.3775 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:
TargetMol | Animal experiments For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent 10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH2O , the resulting working solution concentration would be 2 mg/mL.
Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSOTargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSOTargetMol | reagent stock solution to 400 μL PEG300TargetMol | reagent and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH2OTargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.
All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.
1 Enter information below:
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2 Enter the in vivo formulation:
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%
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