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Anti-Human CD3 Antibody (2E161) is a Mouse antibody targeting Human CD3. Anti-Human CD3 Antibody (2E161) can be used in FCM.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μg | $123 | 7-10 days | 7-10 days |
| Description | Anti-Human CD3 Antibody (2E161) is a Mouse antibody targeting Human CD3. Anti-Human CD3 Antibody (2E161) can be used in FCM. |
| Synonyms | cluster of differentiation 3, CD3 |
| Ig Type | IgG2a |
| Clone | 2E161 |
| Reactivity | Human |
| Specificity | human CD3 |
| Application | |
| Recommended Dose | FCM: ≤ 0.25 µg per million cells in 100 µl volume. It is strongly recommended that the reagent should be titrated for optimal performance for each application. |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Purification | Protein A affinity column |
| Appearance | Liquid |
| Formulation | Supplied in 10 mM Sodium Citrate, 150 mM NaCl, 0.02 mg/ml Polysorbate 80, pH 5.0. |
| Endotoxin | < 0.5 EU/μg by gel clotting method |
| Concentration | 1 mg/mL |
| Research Background | CD3 is a member of the immunoglobulin superfamily, expressed on T cells. It is composed of four distinct chains (ε, γ, δ, ζ). CD3 antigen can form a complex with the T cell receptor (TCR) to generate an activation signal in T cells, which plays an important role in TCR signal transduction and both cytotoxic T cell (CD8 + naïve T cells) and T helper cells (CD4+ naïve T cells) activation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant human CD3 |
| Stability & Storage | Store at 2°C-8°C for 12 months, do not freeze. |
| Transport | Shipping with blue ice. |
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