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Anti-IL-17RA Antibody (3M821)
😃Good
Catalog No. TMAY-01301
Alias interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Anti-IL-17RA Antibody (3M821) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (3M821) can be used in ELISA,ELISA(Cap),WB.
Anti-IL-17RA Antibody (3M821)
Anti-IL-17RA Antibody (3M821)
😃Good
Catalog No. TMAY-01301Alias interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Anti-IL-17RA Antibody (3M821) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (3M821) can be used in ELISA,ELISA(Cap),WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $199 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-17RA Antibody (3M821) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (3M821) can be used in ELISA,ELISA(Cap),WB. |
| Synonyms | interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5 |
| Ig Type | Mouse IgG1 |
| Clone | 3M821 |
| Reactivity | Human |
| Specificity | Human IL-17RA |
| Verified Activity | Anti-IL17RA mouse monoclonal antibody at 1:500 dilution. -Lane A: Hela Whole Cell lysate. -Lysates/proteins at 30 μg per lane. -Secondary -Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution. -Developed using the Odyssey technique. -Performed under reducing conditions. -Predicted band size:96 kDa. -Observed band size:105 kDa(We are unsure as to the identity of these extra bands.) |
| Application | |
| Recommended Dose | WB: 1:500-1:1000; ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17RA (rh IL17RA; TMPY-01371; NP_055154.3; Met 1-Trp 320). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Interleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human IL17RA protein (TMPY-01371) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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