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Anti-IL-17RA Antibody (3M821) (Synonyms: interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217|...)

Catalog No. TMAY-01301 Copy Product Info
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Anti-IL-17RA Antibody (3M821) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (3M821) can be used in ELISA,ELISA(Cap),WB.

Anti-IL-17RA Antibody (3M821)

Copy Product Info
🥰Excellent
Catalog No. TMAY-01301
Synonyms interleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5

Anti-IL-17RA Antibody (3M821) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (3M821) can be used in ELISA,ELISA(Cap),WB.

Anti-IL-17RA Antibody
(3M821)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1997-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IL-17RA Antibody (3M821) is a Mouse antibody targeting IL-17RA. Anti-IL-17RA Antibody (3M821) can be used in ELISA,ELISA(Cap),WB.
Synonymsinterleukin 17 receptor A, IL-17RA, IL17R, hIL-17R, CDw217, CD217, CANDF5
Ig Type
Mouse IgG1
Clone
3M821
Reactivity
Human
Specificity
Human IL-17RA
Verified Activity
Anti-IL17RA mouse monoclonal antibody at 1:500 dilution.
-Lane A: Hela Whole Cell lysate.
-Lysates/proteins at 30 μg per lane.
-Secondary
-Goat Anti-Mouse IgG H&L (Dylight800) at 1/15000 dilution.
-Developed using the Odyssey technique.
-Performed under reducing conditions.
-Predicted band size:96 kDa.
-Observed band size:105 kDa(We are unsure as to the identity of these extra bands.)
Application
Recommended Dose
WB: 1:500-1:1000; ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL17RA (rh IL17RA; TMPY-01371; NP_055154.3; Met 1-Trp 320). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundInterleukin-17 receptor (IL-17R), also known as Interleukin-17 receptor A (IL-17RA) and CD217 antigen (CD217), is a cytokine receptor that binds interleukin 17. IL-17R/IL-17RA (CD217) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R/IL-17RA (CD217) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor IL-17RA play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure. Defects in IL-17R/IL-17RA (CD217) are the cause of familial candidiasis type 5 (CANDF5). CANDF5 is a rare disorder with altered immune responses and impaired clearance of fungal infections, selective against Candida. It is characterized by persistent and/or recurrent infections of the skin, nails, and mucous membranes caused by organisms of the genus Candida, mainly Candida albicans.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human IL17RA protein (TMPY-01371)
Antigen Species
Human
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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