Shopping Cart
- Remove All
- Your shopping cart is currently empty
Anti-STAT6 Antibody (7Y861) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (7Y861) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $198 | 7-10 days |
Description | Anti-STAT6 Antibody (7Y861) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (7Y861) can be used in ELISA. |
Alias | STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644 |
Ig Type | Monoclonal Mouse IgG2a |
Clone | 7Y861 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human STAT6 (rh STAT6; TMPY-02603; P42226-1; Met1-Trp847). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-κB and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggests that the direct interaction between Stat6 and NF-κB may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-κB. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human STAT6 protein (TMPY-02603) |
Antigen Species | Human |
Biology Area | Apoptosis Transcription Factors and Regulators |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.