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Anti-STAT6 Antibody (7Y861)
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Catalog No. TMAY-02526
Alias STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644
Anti-STAT6 Antibody (7Y861) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (7Y861) can be used in ELISA.
Anti-STAT6 Antibody (7Y861)
Anti-STAT6 Antibody (7Y861)
😃Good
Catalog No. TMAY-02526Alias STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644
Anti-STAT6 Antibody (7Y861) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (7Y861) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $198 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-STAT6 Antibody (7Y861) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (7Y861) can be used in ELISA. |
| Synonyms | STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644 |
| Ig Type | Mouse IgG2a |
| Clone | 7Y861 |
| Reactivity | Human |
| Specificity | Human STAT6 No cross-reactivity in ELISA with Baculovirus cell lysate |
| Application | |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human STAT6 (rh STAT6; TMPY-02603; P42226-1; Met1-Trp847). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Signal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-κB and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggests that the direct interaction between Stat6 and NF-κB may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-κB. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human STAT6 protein (TMPY-02603) |
| Antigen Species | Human |
| Biology Area | Apoptosis Transcription Factors and Regulators |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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