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Anti-STAT6 Antibody (7Y861) (Synonyms: STAT6C, STAT6B, signal transducer and activator of transcription 6, int...)

Catalog No. TMAY-02526 Copy Product Info
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Anti-STAT6 Antibody (7Y861) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (7Y861) can be used in ELISA.

Anti-STAT6 Antibody (7Y861)

Copy Product Info
🥰Excellent
Catalog No. TMAY-02526
Synonyms STAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644

Anti-STAT6 Antibody (7Y861) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (7Y861) can be used in ELISA.

Anti-STAT6 Antibody
(7Y861)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$1987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-STAT6 Antibody (7Y861) is a Mouse antibody targeting STAT6. Anti-STAT6 Antibody (7Y861) can be used in ELISA.
SynonymsSTAT6C, STAT6B, signal transducer and activator of transcription 6, interleukin-4 induced, IL-4-STAT, D12S1644
Ig Type
Mouse IgG2a
Clone
7Y861
Reactivity
Human
Specificity
Human STAT6
No cross-reactivity in ELISA with
Baculovirus cell lysate
Application
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human STAT6 (rh STAT6; TMPY-02603; P42226-1; Met1-Trp847). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundSignal transducer and activator of transcription 6 (STAT6) is a transcription factor that is activated by interleukin-4 (IL-4)-induced tyrosine phosphorylation and mediates most of the IL-4-induced gene expression. STAT6 plays a central role in exerting interleukin-4 (IL-4) mediated biological responses and is found to induce the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. Transcriptional activation by STAT6 requires the interaction with coactivators like p300 and the CREB-binding protein (CBP). NF-κB and tyrosine-phosphorylated Stat6 can directly bind each other in vitro and in vivo, which suggests that the direct interaction between Stat6 and NF-κB may provide a basis for synergistic activation of transcription by IL-4 and activators of NF-κB.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: Human STAT6 protein (TMPY-02603)
Antigen Species
Human
Biology Area
Apoptosis Transcription Factors and Regulators
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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