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N3-C2-NHS ester

Name: N3-C2-NHS ester
Brand: TargetMol
SKU: T18465
Price: 32 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T18465Cas No. 850180-76-6

Alias 3-Azidopropanoic acid NHS ester

N3-C2-NHS ester (3-Azidopropanoic acid NHS ester) is an ADC linker, which is a cross-linking agent for macromolecular compounds, and can be used for the synthesis of antibody-coupled reactive molecules (ADCs).

N3-C2-NHS ester

🥰Excellent

Catalog No. T18465Alias 3-Azidopropanoic acid NHS esterCas No. 850180-76-6

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
5 mg	$32	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Product Introduction

Bioactivity

Description	N3-C2-NHS ester (3-Azidopropanoic acid NHS ester) is an ADC linker, which is a cross-linking agent for macromolecular compounds, and can be used for the synthesis of antibody-coupled reactive molecules (ADCs).
Synonyms	3-Azidopropanoic acid NHS ester

Chemical Properties

Molecular Weight	212.16
Formula	C₇H₈N₄O₄
Cas No.	850180-76-6
Smiles	[N-]=[N+]=NCCC(=O)ON1C(=O)CCC1=O
Relative Density.	1.31g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 80.00 mg/mL (377.07 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.7134 mL	23.5671 mL	47.1342 mL	235.6712 mL
5 mM	0.9427 mL	4.7134 mL	9.4268 mL	47.1342 mL
10 mM	0.4713 mL	2.3567 mL	4.7134 mL	23.5671 mL
20 mM	0.2357 mL	1.1784 mL	2.3567 mL	11.7836 mL
50 mM	0.0943 mL	0.4713 mL	0.9427 mL	4.7134 mL
100 mM	0.0471 mL	0.2357 mL	0.4713 mL	2.3567 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc