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Anti-IL-17 Antibody (1L175) is a Rabbit antibody targeting IL-17. Anti-IL-17 Antibody (1L175) can be used in ELISA,ELISA(Cap).
Pack Size | Price | Availability | Quantity |
---|---|---|---|
20 μL | $92 | 7-10 days | |
100 μL | $270 | 7-10 days |
Description | Anti-IL-17 Antibody (1L175) is a Rabbit antibody targeting IL-17. Anti-IL-17 Antibody (1L175) can be used in ELISA,ELISA(Cap). |
Alias | interleukin 17A |
Ig Type | Monoclonal Rabbit IgG |
Clone | 1L175 |
Reactivity | Mouse |
Application | ELISA,ELISA(Cap) |
Recommended Dose | ELISA: 1:5000-1:10000; ELISA(Cap): 1:250-1:2000 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Mouse IL17 / IL17a (rM IL17 / IL17a; TMPY-02900; Q62386; Thr22-Ala158). |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | IL17, also known as IL17a, is a cytokine that belongs to the IL-17 family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. The IL-17 family of cytokines includes six members, IL-17/IL-17A, IL-17B, IL-17C, IL-17D, IL-17E/IL-25, and IL-17F, which are produced by multiple cell types. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of IL-17 are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis, and multiple sclerosis.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy |
Conjucates | Unconjugated |
Immunogen | Recombinant Mouse IL17 / IL17a Protein (TMPY-02900) |
Antigen Species | Mouse |
Biology Area | Neuroinflammation |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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