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Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301)
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Catalog No. TMAB-07758
Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) is a Mouse antibody targeting Interleukin-1 receptor-like 1/ST2. Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) can be used in WB.
Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301)
Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301)
😃Good
Catalog No. TMAB-07758
Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) is a Mouse antibody targeting Interleukin-1 receptor-like 1/ST2. Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 200 μg | $1,058 | 7-10 days | 7-10 days | |
| 50 μL | $221 | 7-10 days | 7-10 days | |
| 100 μL | $372 | 7-10 days | 7-10 days | |
| 200 μL | $527 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Antigen Details
Chemical Properties
| Description | Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) is a Mouse antibody targeting Interleukin-1 receptor-like 1/ST2. Anti-Interleukin-1 receptor-like 1/ST2 Antibody (1K301) can be used in WB. |
| Ig Type | IgG |
| Clone | 1K301 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Isoform C: Cell membrane.Isoform B: Secreted. Cell membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Highly expressed in kidney, lung, placenta, stomach, skeletal muscle, colon and small intestine. Isoform A is prevalently expressed in the lung, testis, placenta, stomach and colon. Isoform B is more abundant in the brain, kidney and the liver. Isoform C is not detected in brain, heart, liver, kidney and skeletal muscle. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein A purified |
| Appearance | Liquid |
| Formulation | 0.01M PBS (pH7.4). |
| Research Background | ST2 is a member of a superfamily containing the Interleukin 1 (IL1) receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF. More recently, it has been shown to negatively regulate IL1 receptor and Toll-like receptor 4 (TLR4) signaling and to maintain endotoxin tolerance. It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP. |
| Immunogen | Recombinant Protein: human human Interleukin-1 receptor-like 1/ST2 protein |
| Antigen Species | Human |
| Gene Name | IL1RL1 |
| Gene ID | |
| Protein Name | Interleukin-1 receptor-like 1 |
| Uniprot ID | |
| Function | Receptor for interleukin-33 (IL-33), its stimulation recruits MYD88, IRAK1, IRAK4, and TRAF6, followed by phosphorylation of MAPK3/ERK1 and/or MAPK1/ERK2, MAPK14, and MAPK8. Possibly involved in helper T-cell function. |
| Molecular Weight | Theoretical: 61 kDa. |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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