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Thiambutosine

Name: Thiambutosine
Brand: TargetMol
SKU: T19868
Price: 132 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T19868Cas No. 500-89-0

Alias CIBA1906

Thiambutosine exhibits inhibitory activity against Mycobacterium leprae and mushroom tyrosinase, making it suitable for infection studies.

Thiambutosine

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Purity: 99.95%

Catalog No. T19868Alias CIBA1906Cas No. 500-89-0

Thiambutosine exhibits inhibitory activity against Mycobacterium leprae and mushroom tyrosinase, making it suitable for infection studies.

Pack Size	Price	USA Warehouse	Global Warehouse
25 mg	$132	-	In Stock
50 mg	$211	-	In Stock
100 mg	$334	6-8 weeks	6-8 weeks

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.95%

Appearance:Solid

Color:Yellow

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COA HNMR LCMS

Product Introduction

Bioactivity

Description	Thiambutosine exhibits inhibitory activity against Mycobacterium leprae and mushroom tyrosinase, making it suitable for infection studies.
In vitro	Thiambutosine exhibits antibacterial activity against mycobacteria, with a half-maximal effective concentration (EC₅₀) of 11 μg/mL against Leishmania amazonensis [1].
Synonyms	CIBA1906

Chemical Properties

Molecular Weight	343.49
Formula	C₁₉H₂₅N₃OS
Cas No.	500-89-0
Smiles	CCCCOc1ccc(NC(=S)Nc2ccc(cc2)N(C)C)cc1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (291.13 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.9113 mL	14.5565 mL	29.1129 mL	145.5646 mL
5 mM	0.5823 mL	2.9113 mL	5.8226 mL	29.1129 mL
10 mM	0.2911 mL	1.4556 mL	2.9113 mL	14.5565 mL
20 mM	0.1456 mL	0.7278 mL	1.4556 mL	7.2782 mL
50 mM	0.0582 mL	0.2911 mL	0.5823 mL	2.9113 mL
100 mM	0.0291 mL	0.1456 mL	0.2911 mL	1.4556 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc