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Nemolizumab (Synonyms: CIM331)

Catalog No. T76724 Copy Product Info
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Nemolizumab (CIM331) is a humanized monoclonal antibody targeting the human interleukin-31 receptor A, inhibiting IL-31 binding and subsequent signal transduction. It is useful for studying atopic dermatitis with pruritus.

Nemolizumab

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Catalog No. T76724
Synonyms CIM331

Nemolizumab (CIM331) is a humanized monoclonal antibody targeting the human interleukin-31 receptor A, inhibiting IL-31 binding and subsequent signal transduction. It is useful for studying atopic dermatitis with pruritus.

Nemolizumab
Cas No. 1476039-58-3
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Pack SizePriceUSA StockGlobal StockQuantity
1 mg$143In StockIn Stock
5 mg$343In StockIn Stock
10 mg$562-In Stock
25 mg$889-In Stock
50 mg$1,190-In Stock
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:100% (SEC-HPLC)
Appearance:Liquid
Color:Transparent
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Product Introduction

Bioactivity
Description
Nemolizumab (CIM331) is a humanized monoclonal antibody targeting the human interleukin-31 receptor A, inhibiting IL-31 binding and subsequent signal transduction. It is useful for studying atopic dermatitis with pruritus.
SynonymsCIM331
Reactivity
Human
Verified Activity
Immobilized Human IL-31RA Protein (Fc) at 2 μg/mL (30 μL/well) can bind Nemolizumab. The EC50 is 20.79 ng/mL.
verifiedActivity
Application
Functional assay
Antibody Type
Monoclonal
FormulationSupplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition.
Endotoxin<1.0 EU/mg
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Gene ID
Uniprot ID
TargetIL-31Ra
Chemical Properties
Molecular Weight144.92 kDa
Cas No.1476039-58-3
Antibody Information
IsotypeHuman IgG2 kappa
Recommended Isotype Control
Storage & Solubility Information
Storagestore at low temperature | -20°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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