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Anti-IL-10R beta/IL-10RB Antibody (6Y486)
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Catalog No. TMAY-01368
Alias interleukin 10 receptor, β, interleukin 10 receptor, beta
Anti-IL-10R beta/IL-10RB Antibody (6Y486) is a Mouse antibody targeting IL-10R beta/IL-10RB. Anti-IL-10R beta/IL-10RB Antibody (6Y486) can be used in ELISA.
Anti-IL-10R beta/IL-10RB Antibody (6Y486)
Anti-IL-10R beta/IL-10RB Antibody (6Y486)
😃Good
Catalog No. TMAY-01368Alias interleukin 10 receptor, β, interleukin 10 receptor, beta
Anti-IL-10R beta/IL-10RB Antibody (6Y486) is a Mouse antibody targeting IL-10R beta/IL-10RB. Anti-IL-10R beta/IL-10RB Antibody (6Y486) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $199 | 7-10 days |
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Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-10R beta/IL-10RB Antibody (6Y486) is a Mouse antibody targeting IL-10R beta/IL-10RB. Anti-IL-10R beta/IL-10RB Antibody (6Y486) can be used in ELISA. |
| Alias | interleukin 10 receptor, β, interleukin 10 receptor, beta |
| Ig Type | Monoclonal Mouse IgG1 |
| Clone | 6Y486 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:1000-1:2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human IL10RB extracellular domain (rh IL10RB; TMPY-01236; NP_000619.3; Met 1-Ser 220). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS with 0.02% Tween 80, pH 7.0 |
| Research Background | Interleukin 10 receptor, beta subunit (IL10RB/IL-10RB) also known as Cytokine receptor family 2 member 4, Interleukin-10 receptor subunit 2, and cytokine receptor family II, member 4, is a subunit for the interleukin-10 receptor. IL10RB/IL-10RB belongs to the cytokine receptor family. It is an accessory chain essential for the active interleukin 10 receptor complex. Coexpression of this and IL10RA proteins is required for IL10-induced signal transduction. Defects in IL10RB/IL-10RB are the cause of inflammatory bowel disease type 25 (IBD25). It is a chronic, relapsing inflammation of the gastrointestinal tract with a complex etiology. It is subdivided into Crohn's disease and ulcerative colitis phenotypes. Crohn's disease may affect any part of the gastrointestinal tract from the mouth to the anus, but most frequently it involves the terminal ileum and colon. Bowel inflammation is transmural and discontinuous; it may contain granulomas or be associated with intestinal or perianal fistulas. In contrast, in ulcerative colitis, the inflammation is continuous and limited to rectal and colonic mucosal layers; fistulas and granulomas are not observed. Both diseases include extraintestinal inflammation of the skin, eyes, or joints. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human IL10RB protein (TMPY-01236) |
| Antigen Species | Human |
| Biology Area | Neuroinflammation |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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