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Levomepromazine-d6 hydrochloride (Methotrimeprazine-d6 hydrochloride) is the deuterium-labeled derivative of Levomepromazine hydrochloride. Levomepromazine (Methotrimeprazine) hydrochloride is an orally active antipsychotic compound that also induces Ca2+ release. It inhibits the SERCA pump, leading to elevated cytosolic Ca2+ levels, and antagonizes multiple neurotransmitter receptors, including dopaminergic, cholinergic, serotonin, and histamine receptors. Additionally, Levomepromazine hydrochloride induces adaptive endoplasmic reticulum stress and autophagy (autophagy), while also exhibiting antiviral, anti-inflammatory, neuroprotective, analgesic, and anti-nociceptive properties. It is utilized in the study of psychiatric disorders and the alleviation of nausea and vomiting.
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| 10 mg | Inquiry | Inquiry | Inquiry | |
| 50 mg | Inquiry | Inquiry | Inquiry |
| Description | Levomepromazine-d6 hydrochloride (Methotrimeprazine-d6 hydrochloride) is the deuterium-labeled derivative of Levomepromazine hydrochloride. Levomepromazine (Methotrimeprazine) hydrochloride is an orally active antipsychotic compound that also induces Ca2+ release. It inhibits the SERCA pump, leading to elevated cytosolic Ca2+ levels, and antagonizes multiple neurotransmitter receptors, including dopaminergic, cholinergic, serotonin, and histamine receptors. Additionally, Levomepromazine hydrochloride induces adaptive endoplasmic reticulum stress and autophagy (autophagy), while also exhibiting antiviral, anti-inflammatory, neuroprotective, analgesic, and anti-nociceptive properties. It is utilized in the study of psychiatric disorders and the alleviation of nausea and vomiting. |
| Synonyms | Methotrimeprazine-d6 hydrochloride |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
Dissolve 2 mg of the compound in 100 μL DMSO
to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.
1) Add 100 μL of the DMSO
stock solution to 400 μL PEG300
and mix thoroughly until the solution becomes clear.
2) Add 50 μL Tween 80 and mix well until fully clarified.
3) Add 450 μL Saline,PBS or ddH2O
and mix thoroughly until a homogeneous solution is obtained.
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