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Anti-UCHL3 Antibody (8N907)
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Catalog No. TMAY-01946
Alias ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Anti-UCHL3 Antibody (8N907) is a Rabbit antibody targeting UCHL3. Anti-UCHL3 Antibody (8N907) can be used in ELISA.
Anti-UCHL3 Antibody (8N907)
Anti-UCHL3 Antibody (8N907)
😃Good
Catalog No. TMAY-01946Alias ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
Anti-UCHL3 Antibody (8N907) is a Rabbit antibody targeting UCHL3. Anti-UCHL3 Antibody (8N907) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 100 μL | $269 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-UCHL3 Antibody (8N907) is a Rabbit antibody targeting UCHL3. Anti-UCHL3 Antibody (8N907) can be used in ELISA. |
| Alias | ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase) |
| Ig Type | Monoclonal Rabbit IgG |
| Clone | 8N907 |
| Reactivity | Human |
| Application | ELISA |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human UCHL3 (rh UCHL3; TMPY-01548; NP_005993.1; Glu 2-Ala 230). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Ubiquitin carboxyl-terminal hydrolase isozyme L3, also known as UCH-L3, Ubiquitin thioesterase L3 and UCHL3, is a ubiquitin-protein hydrolase that belongs to the peptidase C12 family. It is involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C-terminal glycine of either ubiquitin or NEDD8. UCHL3 is highly expressed in heart, skeletal muscle, and testis. UCHL1 and UCHL3 are two of the deubiquitinating enzymes expressed in the brain. These phenotypes indicate the importance of UCHL1 and UCHL3 in the regulation of the central nervous system. UCHL3 functions as a de-ubiquitinating enzyme where lack of its hydrolase activity may result in the prominent accumulation of ubiquitinated proteins and subsequent induction of stress responses in skeletal muscle. UCHL3 has also been identified as a tumor-specific antigen in colon cancer. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Human UCHL3 Protein (TMPY-01548) |
| Antigen Species | Human |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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