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Anti-IFN gamma Antibody (3Z483) (Synonyms: interferon, γ, interferon, gamma, IFN γ)

Catalog No. TMAY-03419 Copy Product Info
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Anti-IFN gamma Antibody (3Z483) is a Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody (3Z483) can be used in FCM.

Anti-IFN gamma Antibody (3Z483)

Copy Product Info
🥰Excellent
Catalog No. TMAY-03419
Synonyms interferon, γ, interferon, gamma, IFN γ

Anti-IFN gamma Antibody (3Z483) is a Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody (3Z483) can be used in FCM.

Anti-IFN gamma Antibody
(3Z483)
Pack SizePriceUSA StockGlobal StockQuantity
100 μL$2697-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-IFN gamma Antibody (3Z483) is a Rabbit antibody targeting IFN gamma. Anti-IFN gamma Antibody (3Z483) can be used in FCM.
Synonymsinterferon, γ, interferon, gamma, IFN γ
Ig Type
Rabbit IgG
Clone
3Z483
Reactivity
Mouse
Specificity
Mouse IFN gamma
Verified Activity
Flow cytometric analysis of Mouse Interferon gamma expression on BABL/c splenocytes. BABL/c splenocytes were stimulated for 4-6 hours with PMA and Ionomycin in the presence of GolgiPlug. The cells were treated according to manufacturer’s manual (BD Pharmingen™ Cat. No. 554714), stained with purified anti-Mouse Interferon gamma, then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of intact cells.
Application
Recommended Dose
FCM: 1:25-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionThis antibody was obtained from a rabbit immunized with purified, recombinant Mouse Interferon Gamma / IFNG (rM Interferon Gamma / IFNG; TMPY-03356; NP_032363.1; Met1-Cys155).
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundIFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activator of macrophages and has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. The IFNG monomer consists of a core of six α-helices and an extended unfolded sequence in the C-terminal region. IFN gamma is critical for innate and adaptive immunity against viral and intracellular bacterial infections and tumor control. Aberrant IFN gamma expression is associated with some autoinflammatory and autoimmune diseases. The importance of IFN gamma in the immune system stems in part from its ability to inhibit viral replication directly, and most importantly from its immunostimulatory and immunomodulatory effects. IFNG also promotes NK cell activity.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Others Formats
APC/FITC/PE
Antibody Types Available
4
Antigen Details
Immunogen
Recombinant Protein: Mouse Interferon Gamma / IFNG Protein (TMPY-03356)
Antigen Species
Mouse
Biology Area
Neuroinflammation
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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