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Tazobactam sodium

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Catalog No. T1262LCas No. 89785-84-2
Alias Tazobactam (sodium salt)

Tazobactam sodium primarily functions to inhibit β-lactamase enzymes produced by bacteria.

Tazobactam sodium
Other Forms of Tazobactam sodium:
TazobactamT126289786-04-9
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Tazobactam sodium

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Purity: 98.56%
Catalog No. T1262LAlias Tazobactam (sodium salt)Cas No. 89785-84-2
Tazobactam sodium primarily functions to inhibit β-lactamase enzymes produced by bacteria.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
100 mg$40-In Stock
500 mg$92-In Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:98.56%
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Product Introduction

Bioactivity
Description
Tazobactam sodium primarily functions to inhibit β-lactamase enzymes produced by bacteria.
In vitro
Tazobactam sodium (5 μg/mL, 18 hours) inhibited bacterial growth in a dose-dependent manner.[1]
In vivo
Tazobactam sodium (1000 mg/kg, intraperitoneally, four times a day, 36-84 hours) in BALB/c mice can reduce the number of bacteria in the mice and can also keep the mice alive at low doses. [1]
SynonymsTazobactam (sodium salt)
Chemical Properties
Molecular Weight322.27
FormulaC10H11N4NaO5S
Cas No.89785-84-2
Smiles[Na+].C[C@]1(CN2C=CN=N2)[C@@H](N2[C@@H](CC2=O)S1(=O)=O)C([O-])=O
Relative Density.1.92 g/cm3
Storage & Solubility Information
Storagekeep away from direct sunlight,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
H2O: 200 mg/mL (620.6 mM), Sonication is recommended.
DMSO: ≥ 160 mg/mL, Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween-80+45% Saline: 5 mg/mL (15.51 mM), Sonication is recommeded.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM3.1030 mL15.5149 mL31.0299 mL155.1494 mL
5 mM0.6206 mL3.1030 mL6.2060 mL31.0299 mL
10 mM0.3103 mL1.5515 mL3.1030 mL15.5149 mL
20 mM0.1551 mL0.7757 mL1.5515 mL7.7575 mL
50 mM0.0621 mL0.3103 mL0.6206 mL3.1030 mL
100 mM0.0310 mL0.1551 mL0.3103 mL1.5515 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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